Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.3487 | 0.3487 |
Brugia malayi | TAR-binding protein | 0.0074 | 0.6192 | 0.6192 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0101 | 1 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0101 | 1 | 1 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.003 | 0 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.3487 | 0.3487 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 1 | 1 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.003 | 0 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.1068 | 0.1068 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0071 | 0.5844 | 0.5844 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0101 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.6192 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.6421 | 0.6421 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0101 | 1 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0075 | 0.6421 | 0.6421 |
Brugia malayi | RNA binding protein | 0.0074 | 0.6192 | 0.6192 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.003 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.3487 | 0.3487 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0071 | 0.5844 | 0.5844 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.003 | 0 | 0.5 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0101 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0101 | 1 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0075 | 0.6421 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 1 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0101 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.6192 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.6192 | 1 |
Onchocerca volvulus | 0.0101 | 1 | 1 | |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0071 | 0.5844 | 0.5844 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0101 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.6192 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 1 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0075 | 0.6421 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0101 | 1 | 1 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.003 | 0 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0101 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.1068 | 0.1725 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0101 | 1 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0101 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0074 | 0.6192 | 0.6192 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.003 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.6421 | 0.6421 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1068 | 0.1068 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0075 | 0.6421 | 0.6421 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0101 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0101 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.6421 | 0.6421 |
Brugia malayi | AMP-binding enzyme family protein | 0.0101 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0074 | 0.6192 | 0.6192 |
Toxoplasma gondii | propionate-CoA ligase | 0.003 | 0 | 0.5 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.003 | 0 | 0.5 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.003 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 1 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.003 | 0 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0074 | 0.6192 | 0.6192 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0075 | 0.6421 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.6421 | 0.6421 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0101 | 1 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0101 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.6192 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0074 | 0.6192 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.3487 | 0.3487 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0071 | 0.5844 | 0.5844 |
Echinococcus granulosus | tar DNA binding protein | 0.0074 | 0.6192 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0101 | 1 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0101 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0074 | 0.6192 | 0.6192 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.003 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.6421 | 0.6421 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.