Detailed information for compound 1186404

Basic information

Technical information
  • TDR Targets ID: 1186404
  • Name: N-(4-methoxyphenyl)hexadecanamide
  • MW: 361.561 | Formula: C23H39NO2
  • H donors: 1 H acceptors: 1 LogP: 8.4 Rotable bonds: 17
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCCCC(=O)Nc1ccc(cc1)OC
  • InChi: 1S/C23H39NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-23(25)24-21-17-19-22(26-2)20-18-21/h17-20H,3-16H2,1-2H3,(H,24,25)
  • InChiKey: FTOITOZVQYKKNO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(4-methoxyphenyl)palmitamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Beta tubulin 0.0094 0.2612 0.5
Toxoplasma gondii beta-tubulin, putative 0.0094 0.2612 0.5
Schistosoma mansoni tubulin subunit beta 0.0094 0.2612 0.2612
Leishmania major beta tubulin 0.0094 0.2612 0.5
Leishmania major beta tubulin 0.0094 0.2612 0.5
Leishmania major beta tubulin 0.0094 0.2612 0.5
Trypanosoma brucei beta tubulin 0.0094 0.2612 0.5
Echinococcus granulosus Tubulin beta 2C chain 0.0094 0.2612 0.2612
Trichomonas vaginalis tubulin, putative 0.0094 0.2612 0.5
Toxoplasma gondii beta-1 tubulin, putative 0.0094 0.2612 0.5
Trypanosoma brucei beta tubulin 0.0094 0.2612 0.5
Brugia malayi beta-tubulin, identical 0.0094 0.2612 1
Loa Loa (eye worm) beta-tubulin 0.0094 0.2612 1
Leishmania major beta tubulin 0.0094 0.2612 0.5
Leishmania major beta tubulin 0.0094 0.2612 0.5
Echinococcus multilocularis Tubulin beta 2C chain 0.0094 0.2612 0.2612
Leishmania major beta tubulin 0.0094 0.2612 0.5
Echinococcus multilocularis Tubulin beta 2C chain 0.0094 0.2612 0.2612
Leishmania major beta tubulin 0.0094 0.2612 0.5
Echinococcus multilocularis tubulin beta 1 chain 0.0094 0.2612 0.2612
Entamoeba histolytica tubulin family protein 0.0094 0.2612 0.5
Schistosoma mansoni tubulin subunit beta 0.0094 0.2612 0.2612
Leishmania major beta tubulin 0.0094 0.2612 0.5
Echinococcus multilocularis Tubulin beta 2C chain 0.0094 0.2612 0.2612
Leishmania major beta tubulin 0.0094 0.2612 0.5
Trichomonas vaginalis tubulin epsilon chain, putative 0.0094 0.2612 0.5
Schistosoma mansoni tubulin subunit beta 0.0094 0.2612 0.2612
Echinococcus multilocularis beta tubulin 0.0094 0.2612 0.2612
Echinococcus granulosus tubulin subunit beta 0.0094 0.2612 0.2612
Giardia lamblia Beta tubulin 0.0094 0.2612 0.5
Trypanosoma cruzi beta tubulin, putative 0.0094 0.2612 0.5
Giardia lamblia Beta tubulin 0.0094 0.2612 0.5
Trichomonas vaginalis tubulin epsilon chain, putative 0.0094 0.2612 0.5
Echinococcus granulosus tubulin beta 1 chain 0.0094 0.2612 0.2612
Brugia malayi Tubulin beta-1 chain 0.0094 0.2612 1
Echinococcus granulosus Tubulin beta 2C chain 0.0094 0.2612 0.2612
Trypanosoma brucei beta tubulin 0.0094 0.2612 0.5
Leishmania major beta tubulin 0.0094 0.2612 0.5
Echinococcus granulosus tubulin beta 4A class IVa 0.0094 0.2612 0.2612
Toxoplasma gondii beta tubulin 0.0094 0.2612 0.5
Echinococcus granulosus beta tubulin 0.0094 0.2612 0.2612
Schistosoma mansoni tubulin subunit beta 0.0094 0.2612 0.2612
Echinococcus granulosus beta tubulin 0.0094 0.2612 0.2612
Loa Loa (eye worm) tubulin beta-4 chain 0.0094 0.2612 1
Loa Loa (eye worm) BEN-1 protein 0.0094 0.2612 1
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0094 0.2612 0.2612
Echinococcus multilocularis Tubulin beta 2C chain 0.0094 0.2612 0.2612
Echinococcus granulosus Tubulin beta 2C chain 0.0094 0.2612 0.2612
Loa Loa (eye worm) tubulin beta chain 0.0094 0.2612 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0094 0.2612 0.5
Echinococcus multilocularis Tubulin beta 2C chain 0.0094 0.2612 0.2612
Loa Loa (eye worm) tubulin beta-1 chain 0.0094 0.2612 1
Leishmania major beta tubulin 0.0094 0.2612 0.5
Leishmania major beta tubulin 0.0094 0.2612 0.5
Plasmodium vivax tubulin beta chain, putative 0.0094 0.2612 0.5
Loa Loa (eye worm) BEN-1 protein 0.0094 0.2612 1
Leishmania major beta tubulin 0.0094 0.2612 0.5
Entamoeba histolytica tubulin family protein 0.0094 0.2612 0.5
Loa Loa (eye worm) tubulin beta-2A chain 0.0094 0.2612 1
Echinococcus multilocularis beta tubulin 0.0094 0.2612 0.2612
Leishmania major beta tubulin 0.0094 0.2612 0.5
Leishmania major beta tubulin 0.0094 0.2612 0.5
Leishmania major beta tubulin 0.0094 0.2612 0.5
Leishmania major beta tubulin 0.0094 0.2612 0.5
Trypanosoma brucei beta tubulin 0.0094 0.2612 0.5
Echinococcus multilocularis tubulin subunit beta 0.0094 0.2612 0.2612
Echinococcus granulosus Tubulin beta 2C chain 0.0094 0.2612 0.2612
Trichomonas vaginalis tubulin beta chain, putative 0.0094 0.2612 0.5
Schistosoma mansoni tubulin subunit beta 0.0094 0.2612 0.2612
Echinococcus granulosus Tubulin beta 2C chain 0.0094 0.2612 0.2612
Schistosoma mansoni tubulin subunit beta 0.0094 0.2612 0.2612
Plasmodium falciparum tubulin beta chain 0.0094 0.2612 0.5
Trichomonas vaginalis tubulin gamma chain, putative 0.0094 0.2612 0.5
Leishmania major beta tubulin 0.0094 0.2612 0.5

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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