Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | lamin | 0.0027 | 0.0728 | 0.0728 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0728 | 0.1722 |
Echinococcus granulosus | tissue type plasminogen activator | 0.008 | 0.4231 | 0.4231 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0728 | 0.0728 |
Brugia malayi | Kringle domain containing protein | 0.008 | 0.4231 | 1 |
Toxoplasma gondii | kringle domain-containing protein | 0.008 | 0.4231 | 0.5 |
Schistosoma mansoni | lamin | 0.0027 | 0.0728 | 0.0728 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.2218 | 0.5241 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1191 | 0.1191 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0728 | 0.1722 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0728 | 0.1722 |
Onchocerca volvulus | 0.008 | 0.4231 | 1 | |
Leishmania major | hypothetical protein, conserved | 0.008 | 0.4231 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.2218 | 0.5241 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.4231 | 1 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.4231 | 0.4231 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0728 | 0.1722 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0728 | 0.0728 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0728 | 0.1722 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.1191 | 0.2815 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0728 | 0.0728 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.2218 | 0.5241 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0696 | 0.1646 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.008 | 0.4231 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.2218 | 0.5241 |
Schistosoma mansoni | lamin | 0.0027 | 0.0728 | 0.0728 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.008 | 0.4231 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.008 | 0.4231 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1191 | 0.2815 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.008 | 0.4231 | 0.5 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.008 | 0.4231 | 0.4231 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0728 | 0.0728 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.008 | 0.4231 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0728 | 0.0728 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0728 | 0.0728 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.