Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | chemokine (C-X-C motif) receptor 1 | Starlite/ChEMBL | References |
Homo sapiens | chemokine (C-X-C motif) receptor 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0093 | 0.2958 | 1 |
Echinococcus granulosus | Cystatin B Stefin B | 0.0093 | 0.2958 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0093 | 0.2958 | 1 |
Loa Loa (eye worm) | cystatin | 0.0093 | 0.2958 | 1 |
Echinococcus granulosus | proteinase inhibitor I25 cystatin | 0.0093 | 0.2958 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Onchocerca volvulus | 0.0093 | 0.2958 | 1 | |
Echinococcus multilocularis | proteinase inhibitor I25, cystatin | 0.0093 | 0.2958 | 1 |
Schistosoma mansoni | cystatin B | 0.0093 | 0.2958 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.2958 | 1 |
Brugia malayi | cystatin | 0.0093 | 0.2958 | 1 |
Onchocerca volvulus | 0.0093 | 0.2958 | 1 | |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0 | 0.5 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.2958 | 1 |
Loa Loa (eye worm) | cystatin-type cysteine proteinase inhibitor CPI-1 | 0.0093 | 0.2958 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0 | 0.5 |
Onchocerca volvulus | 0.0093 | 0.2958 | 1 | |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0093 | 0.2958 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Onchocerca volvulus | 0.0093 | 0.2958 | 1 | |
Loa Loa (eye worm) | cysteine protease inhibitor | 0.0093 | 0.2958 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0 | 0.5 |
Brugia malayi | cystatin | 0.0093 | 0.2958 | 1 |
Trichomonas vaginalis | Clan IH, family I25, phytocystatin-like peptidase inhibitor | 0.0093 | 0.2958 | 1 |
Onchocerca volvulus | 0.0093 | 0.2958 | 1 | |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0 | 0.5 |
Onchocerca volvulus | 0.0093 | 0.2958 | 1 | |
Echinococcus multilocularis | Cystatin B (Stefin B) | 0.0093 | 0.2958 | 1 |
Brugia malayi | cystatin-type cysteine proteinase inhibitor CPI-2, putative | 0.0093 | 0.2958 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.