Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1613 | 0.1613 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0036 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.1613 | 0.1613 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0.1613 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.1613 | 0.1613 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0036 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.1613 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.1613 | 0.1613 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.1613 | 0.1613 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.1613 | 0.1613 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.1613 | 0.1613 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1613 | 0.1613 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.1613 | 0.1613 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.1613 | 0.1613 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0.1613 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1613 | 0.1613 |
Onchocerca volvulus | 0.0011 | 0.1613 | 1 | |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.1613 | 1 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0036 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.1613 | 0.1613 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.1613 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.1613 | 0.1613 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.1613 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.1613 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.1613 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.1613 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.1613 | 0.1613 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.1613 | 0.1613 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.1613 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0.1613 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.1613 | 0.1613 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.1613 | 0.1613 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.1613 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.1613 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1613 | 0.1613 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.1613 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.1613 | 0.1613 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.1613 | 0.1613 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0036 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.1613 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.1613 | 0.1613 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.1613 | 0.1613 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.1613 | 0.1613 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0036 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.1613 | 0.1613 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0036 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.1613 | 0.1613 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.1613 | 1 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0036 | 1 | 1 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0036 | 1 | 1 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0036 | 1 | 1 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0036 | 1 | 1 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0036 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1613 | 0.1613 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1613 | 0.1613 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.1613 | 0.1613 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.1613 | 0.1613 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.1613 | 0.1613 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.