Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.78 ug ml-1 | In vitro antibacterial activity under anaerobic conditions against Pasteurella multocida strain 59A004 | ChEMBL. | 6876079 |
MIC (functional) | = 3.12 ug ml-1 | In vitro antibacterial activity under anaerobic conditions against Escherichia coli strain 51A266 | ChEMBL. | 6876079 |
MIC (functional) | = 3.12 ug ml-1 | In vitro antibacterial activity under anaerobic conditions against Treponema hyodysenteriae strain 94A002 | ChEMBL. | 6876079 |
MIC (functional) | = 3.12 ug ml-1 | In vitro antibacterial activity under anaerobic conditions against Escherichia coli strain 51A266 | ChEMBL. | 6876079 |
MIC (functional) | = 6.25 ug ml-1 | In vitro antibacterial activity under anaerobic conditions against Streptomyces pyogenes strain 2C203 | ChEMBL. | 6876079 |
MIC (functional) | = 6.25 ug ml-1 | In vitro antibacterial activity under anaerobic conditions against Salmonella choleraesuis strain 58B242 | ChEMBL. | 6876079 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.