Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | hypothetical protein, conserved | 0.0535 | 0.5382 | 1 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0101 | 0.0877 | 0.1629 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0101 | 0.0877 | 0.0877 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0877 | 0.1629 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0323 | 0.3184 | 0.5 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0535 | 0.5382 | 1 |
Echinococcus granulosus | ubiquitin conjugating enzyme E2 N | 0.0323 | 0.3184 | 0.5916 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0101 | 0.0877 | 0.1629 |
Echinococcus multilocularis | ubiquitin conjugating enzyme E2 N | 0.0323 | 0.3184 | 0.3184 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.0384 | 0.0713 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.0877 | 0.1629 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Onchocerca volvulus | 0.0101 | 0.0877 | 0.1482 | |
Echinococcus granulosus | enteropeptidase | 0.0101 | 0.0877 | 0.1629 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.0877 | 0.5 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0101 | 0.0877 | 0.0877 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.0384 | 0.0713 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0323 | 0.3184 | 0.5143 |
Schistosoma mansoni | ubiquitin conjugating enzyme 13 | 0.0323 | 0.3184 | 0.5916 |
Leishmania major | hypothetical protein, conserved | 0.0535 | 0.5382 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0093 | 0.0173 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Onchocerca volvulus | 0.0101 | 0.0877 | 0.1482 | |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0535 | 0.5382 | 1 |
Onchocerca volvulus | 0.0535 | 0.5382 | 1 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Brugia malayi | Trypsin family protein | 0.0101 | 0.0877 | 0.1629 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0101 | 0.0877 | 0.1629 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Brugia malayi | Ubiquitin conjugating enzyme protein 13 | 0.0323 | 0.3184 | 0.5916 |
Trypanosoma brucei | ubiquitin-protein ligase, putative | 0.0323 | 0.3184 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0535 | 0.5382 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0877 | 0.1629 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Schistosoma mansoni | hypothetical protein | 0.0535 | 0.5382 | 1 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0323 | 0.3184 | 0.5143 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Toxoplasma gondii | kringle domain-containing protein | 0.0535 | 0.5382 | 1 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0323 | 0.3184 | 0.5916 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0877 | 0.1629 |
Brugia malayi | Kringle domain containing protein | 0.0535 | 0.5382 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0206 | 0.0383 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.0877 | 0.1629 |
Loa Loa (eye worm) | trypsin family protein | 0.0101 | 0.0877 | 0.1629 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0093 | 0.0093 |
Schistosoma mansoni | lamin | 0.0026 | 0.0093 | 0.0173 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0101 | 0.0877 | 0.1629 |
Echinococcus multilocularis | Mastin | 0.0101 | 0.0877 | 0.0877 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0093 | 0.0173 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0323 | 0.3184 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0093 | 0.0173 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0323 | 0.3184 | 0.5916 |
Echinococcus granulosus | Mastin | 0.0101 | 0.0877 | 0.1629 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0101 | 0.0877 | 0.1629 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0093 | 0.0173 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0093 | 0.0093 |
Onchocerca volvulus | 0.0101 | 0.0877 | 0.1482 | |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0877 | 0.1629 |
Brugia malayi | ubiquitin conjugating enzyme protein 13 | 0.0323 | 0.3184 | 0.5916 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0093 | 0.0093 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0101 | 0.0877 | 0.1629 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0206 | 0.0383 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Onchocerca volvulus | 0.0101 | 0.0877 | 0.1482 | |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0877 | 0.1629 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0877 | 0.1629 |
Echinococcus granulosus | lamin | 0.0026 | 0.0093 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0384 | 0.0713 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0093 | 0.0173 |
Brugia malayi | Protein kinase domain containing protein | 0.0535 | 0.5382 | 1 |
Onchocerca volvulus | 0.0101 | 0.0877 | 0.1482 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Brugia malayi | Trypsin family protein | 0.0101 | 0.0877 | 0.1629 |
Entamoeba histolytica | ubiquitin-conjugating enzyme family protein | 0.0323 | 0.3184 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0206 | 0.0383 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0101 | 0.0877 | 0.0877 |
Brugia malayi | Trypsin family protein | 0.0101 | 0.0877 | 0.1629 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.0384 | 0.0713 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0093 | 0.0173 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Brugia malayi | hypothetical protein | 0.0101 | 0.0877 | 0.1629 |
Echinococcus multilocularis | enteropeptidase | 0.0101 | 0.0877 | 0.0877 |
Schistosoma mansoni | lamin | 0.0026 | 0.0093 | 0.0173 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0093 | 0.0173 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0093 | 0.0173 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0101 | 0.0877 | 0.1629 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0101 | 0.0877 | 0.0877 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0535 | 0.5382 | 1 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0535 | 0.5382 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0877 | 0.1629 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0535 | 0.5382 | 0.5382 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0088 | 0.0164 |
Onchocerca volvulus | 0.0101 | 0.0877 | 0.1482 | |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0101 | 0.0877 | 0.1629 |
Brugia malayi | Trypsin family protein | 0.0101 | 0.0877 | 0.1629 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.