CC50 (functional)
|
> 50 uM
|
HepG2 galactose CC50 (uM) Cytotoxicity
|
ChEMBL.
|
No reference
|
IC50 (functional)
|
73.61 uM
|
PubChem BioAssay. Discovery of small molecule inhibitors of the oncogenic and cytokinetic protein MgcRacGAP - Primary and Confirmatory Screens. (Class of assay: confirmatory)
|
ChEMBL.
|
No reference
|
Inhibition (binding)
|
|
Compound was evaluated for the inhibition of human FECH at 10uM
|
MMV_PBOX.
|
No reference
|
MIC (functional)
|
= 0.78 uM
|
AntiMycobacterium tuberculosis activity 1-week GAST/Fe MIC (uM)
|
ChEMBL.
|
No reference
|
MIC (functional)
|
= 1.56 uM
|
AntiMycobacterium tuberculosis activity 2-week GAST/Fe MIC (uM)
|
ChEMBL.
|
No reference
|
MIC (functional)
|
= 6.25 uM
|
AntiMycobacterium tuberculosis activity 1-week 7H9/DPPC/cholesterol/BSA/Tx MIC (uM)
|
ChEMBL.
|
No reference
|
MIC (functional)
|
= 6.25 uM
|
AntiMycobacterium tuberculosis activity 1-week 7H9/cholesterol/BSA/Tx MIC (uM)
|
ChEMBL.
|
No reference
|
MIC (functional)
|
= 6.25 uM
|
AntiMycobacterium tuberculosis activity 2-week Alamar Blue 7H9/cholesterol/BSA/Tx MIC (uM)
|
ChEMBL.
|
No reference
|
MIC (functional)
|
= 6.25 uM
|
AntiMycobacterium tuberculosis activity 2-week Alamar Blue 7H9/ADC/Tw MIC (uM)
|
ChEMBL.
|
No reference
|
MIC (functional)
|
= 6.25 uM
|
AntiMycobacterium tuberculosis activity 2-week 7H9/DPPC/cholesterol/BSA/Tx MIC (uM)
|
ChEMBL.
|
No reference
|
MIC (functional)
|
= 9.4 uM
|
AntiMycobacterium tuberculosis activity 2-week 7H9/ADC/Tw MIC (uM)
|
ChEMBL.
|
No reference
|
MIC (functional)
|
= 9.4 uM
|
AntiMycobacterium tuberculosis activity 2-week 7H9/glucose/BSA/Tx MIC (uM)
|
ChEMBL.
|
No reference
|
MIC (functional)
|
= 9.4 uM
|
AntiMycobacterium tuberculosis activity 1-week 7H9/glucose/BSA/Tx MIC (uM)
|
ChEMBL.
|
No reference
|
MIC (functional)
|
= 12.5 uM
|
AntiMycobacterium tuberculosis activity day 21 MIC99 in 7H9/2.5mM butyrate/pH6/0.1mM nitrite MIC99 (uM)
|
ChEMBL.
|
No reference
|
MIC (functional)
|
= 19 uM
|
AntiMycobacterium tuberculosis activity 1-week 7H9/ADC/Tw MIC (uM)
|
ChEMBL.
|
No reference
|
MIC90 (functional)
|
= 3.12 uM
|
AntiMycobacterium tuberculosis activity day 21 in 7H9/2.5mM butyrate/pH6/0.1mM nitrite MIC90 (uM)
|
ChEMBL.
|
No reference
|
MIC90 (functional)
|
= 3.12 uM
|
AntiMycobacterium tuberculosis activity day 10 in 7H9/2.5mM butyrate/pH6/0.1mM nitrite MIC90 (uM)
|
ChEMBL.
|
No reference
|
MIC90 (functional)
|
= 12.5 uM
|
AntiMycobacterium tuberculosis activity day 10 in 7H9/2.5mM butyrate/pH6/0.1mM nitrite MIC90 (uM)
|
ChEMBL.
|
No reference
|
Potency (functional)
|
= 1.122 um
|
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory)
|
ChEMBL.
|
No reference
|
Potency (functional)
|
1.122 uM
|
PubChem BioAssay. qHTS of GLP-1 Receptor Agonists. (Class of assay: confirmatory)
|
ChEMBL.
|
No reference
|
Potency (functional)
|
1.122 uM
|
PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249]
|
ChEMBL.
|
No reference
|
Potency (functional)
|
= 5.5805 um
|
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen. (Class of assay: confirmatory) [Related pubchem assays: 1473, 1466 ]
|
ChEMBL.
|
No reference
|
Potency (functional)
|
6.5733 uM
|
PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850]
|
ChEMBL.
|
No reference
|
Potency (functional)
|
= 10 um
|
PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory)
|
ChEMBL.
|
No reference
|
Potency (functional)
|
10 uM
|
PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory)
|
ChEMBL.
|
No reference
|
Potency (functional)
|
10 uM
|
PubChem BioAssay. qHTS of Nrf2 Activators. (Class of assay: confirmatory)
|
ChEMBL.
|
No reference
|
Potency (functional)
|
11.6891 uM
|
PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850]
|
ChEMBL.
|
No reference
|
Potency (binding)
|
= 15.8489 um
|
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory)
|
ChEMBL.
|
No reference
|
Potency (functional)
|
20.5962 uM
|
PubChem BioAssay. qHTS of Nrf2 Activators: Hit Validation in Primary Assay. (Class of assay: confirmatory)
|
ChEMBL.
|
No reference
|
Potency (functional)
|
= 22.3872 um
|
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ]
|
ChEMBL.
|
No reference
|
Potency (functional)
|
= 25.1189 um
|
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase). (Class of assay: confirmatory)
|
ChEMBL.
|
No reference
|
Potency (functional)
|
= 31.6228 um
|
PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory)
|
ChEMBL.
|
No reference
|
Potency (functional)
|
31.6228 uM
|
PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory)
|
ChEMBL.
|
No reference
|
Potency (functional)
|
39.8107 uM
|
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404]
|
ChEMBL.
|
No reference
|
Potency (functional)
|
= 56.2341 um
|
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory)
|
ChEMBL.
|
No reference
|
Potency (functional)
|
= 89.1251 um
|
PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)]
|
ChEMBL.
|
No reference
|