Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | Starlite/ChEMBL | References |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 25 nM | Inhibition of lipoprotein associated phospholipase A2 in human plasma | ChEMBL. | 11086729 |
IC50 (binding) | = 25 nM | Inhibition of lipoprotein associated phospholipase A2 in human plasma | ChEMBL. | 11086729 |
Inhibition (binding) | = 10 % | Inhibition of lipoprotein associated phospholipase A2 in human plasma at 300 nM | ChEMBL. | 11086729 |
Inhibition (binding) | = 10 % | Inhibition of Lipoprotein associated phospholipase A2 in rabbit plasma at 1 uM | ChEMBL. | 11086729 |
Inhibition (binding) | = 10 % | Inhibition of lipoprotein associated phospholipase A2 in human plasma at 300 nM | ChEMBL. | 11086729 |
Inhibition (binding) | = 10 % | Inhibition of Lipoprotein associated phospholipase A2 in rabbit plasma at 1 uM | ChEMBL. | 11086729 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.