Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0112 | 0.5 | 0.5 | |
Echinococcus multilocularis | subfamily M14A unassigned peptidase | 0.0112 | 0.5 | 0.5 |
Onchocerca volvulus | Subfamily M14A unassigned peptidase homolog | 0.0112 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0112 | 0.5 | 0.5 | |
Onchocerca volvulus | 0.0112 | 0.5 | 0.5 | |
Schistosoma mansoni | subfamily M14A unassigned peptidase (M14 family) | 0.0112 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0112 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] | ChEMBL. | No reference |
Potency (functional) | 44.6684 uM | PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.