TDR Targets

Basic information

Technical information

TDR Targets ID: 1428536
Name: 1-[(2-methylphenyl)methyl]-1,3-diazinan-2-one
MW: 204.268 | Formula: C12H16N2O
H donors: 1 H acceptors: 1 LogP: 1.54 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: O=C1NCCCN1Cc1ccccc1C
InChi: 1S/C12H16N2O/c1-10-5-2-3-6-11(10)9-14-8-4-7-13-12(14)15/h2-3,5-6H,4,7-9H2,1H3,(H,13,15)
InChiKey: NHWLZSZKXFAFJC-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

1-[(2-methylphenyl)methyl]hexahydropyrimidin-2-one
1-[(2-methylphenyl)methyl]-2-hexahydropyrimidinone
1-(2-methylbenzyl)hexahydropyrimidin-2-one
1-(2-methylbenzyl)tetrahydropyrimidin-2(1H)-one
MLS000095790
SMR000031338
EU-0062780

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	GNAS complex locus	Starlite/ChEMBL	No references
Homo sapiens	microtubule-associated protein tau	Starlite/ChEMBL	No references
Schistosoma mansoni	Thioredoxin glutathione reductase	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma mansoni	microtubule-associated protein tau	Get druggable targets OG5_133504	All targets in OG5_133504
Neospora caninum	Glutathione reductase, related	Get druggable targets OG5_126785	All targets in OG5_126785
Cryptosporidium hominis	thioredoxin reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Plasmodium berghei	glutathione reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium yoelii	thioredoxin reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium vivax	thioredoxin reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma japonicum	ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative	Get druggable targets OG5_131088	All targets in OG5_131088
Plasmodium falciparum	glutathione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Candida albicans	similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase	Get druggable targets OG5_126785	All targets in OG5_126785
Babesia bovis	thiodoxin reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Echinococcus granulosus	microtubule associated protein 2	Get druggable targets OG5_133504	All targets in OG5_133504
Plasmodium falciparum	thioredoxin reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Leishmania donovani	trypanothione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium knowlesi	glutathione reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Leishmania mexicana	trypanothione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Trypanosoma brucei gambiense	trypanothione reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Leishmania major	trypanothione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Loa Loa (eye worm)	thioredoxin reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Leishmania braziliensis	trypanothione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Echinococcus multilocularis	microtubule associated protein 2	Get druggable targets OG5_133504	All targets in OG5_133504
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	Get druggable targets OG5_131088	All targets in OG5_131088
Plasmodium yoelii	glutathione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Schistosoma japonicum	ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative	Get druggable targets OG5_126785	All targets in OG5_126785
Neospora caninum	MGC84926 protein, related	Get druggable targets OG5_126785	All targets in OG5_126785
Cryptosporidium parvum	thioredoxin reductase 1	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium knowlesi	thioredoxin reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Schistosoma japonicum	ko:K04380 microtubule-associated protein tau, putative	Get druggable targets OG5_133504	All targets in OG5_133504
Trypanosoma congolense	trypanothione reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Candida albicans	similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase	Get druggable targets OG5_126785	All targets in OG5_126785
Brugia malayi	glutathione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Leishmania infantum	trypanothione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium berghei	thioredoxin reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	Get druggable targets OG5_126785	All targets in OG5_126785
Brugia malayi	Thioredoxin reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Loa Loa (eye worm)	glutathione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium vivax	glutathione reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Toxoplasma gondii	thioredoxin reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Theileria parva	thioredoxin reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus granulosus	thioredoxin glutathione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Trypanosoma cruzi	trypanothione reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Echinococcus multilocularis	thioredoxin glutathione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Trypanosoma brucei	trypanothione reductase	Get druggable targets OG5_126785	All targets in OG5_126785

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Plasmodium yoelii	dihydrolipoamide dehydrogenase	Thioredoxin glutathione reductase	598 aa	537 aa	24.2 %
Plasmodium berghei	dihydrolipoyl dehydrogenase, apicoplast, putative	Thioredoxin glutathione reductase	598 aa	538 aa	25.3 %
Plasmodium knowlesi	dihydrolipoyl dehydrogenase, apicoplast, putative	Thioredoxin glutathione reductase	598 aa	518 aa	22.0 %
Neospora caninum	glutathione reductase, putative	Thioredoxin glutathione reductase	598 aa	532 aa	34.6 %
Plasmodium vivax	dihydrolipoyl dehydrogenase, apicoplast, putative	Thioredoxin glutathione reductase	598 aa	521 aa	21.5 %
Onchocerca volvulus		Thioredoxin glutathione reductase	598 aa	533 aa	50.8 %
Neospora caninum	Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related	Thioredoxin glutathione reductase	598 aa	512 aa	28.3 %
Toxoplasma gondii	NADPH-glutathione reductase	Thioredoxin glutathione reductase	598 aa	555 aa	33.5 %
Schistosoma mansoni	GTP-binding protein alpha subunit gna	GNAS complex locus	394 aa	450 aa	28.7 %
Plasmodium falciparum	dihydrolipoyl dehydrogenase, apicoplast	Thioredoxin glutathione reductase	598 aa	513 aa	25.0 %
Neospora caninum	hypothetical protein	Thioredoxin glutathione reductase	598 aa	485 aa	30.5 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	aldo-keto reductase, putative	0.0283	0.3016	1
Trypanosoma cruzi	aldo/keto reductase, putative	0.0283	0.3016	1
Mycobacterium tuberculosis	Probable dehydrogenase	0.0104	0.0743	0.2464
Echinococcus granulosus	aldehyde reductase	0.0201	0.1974	0.1968
Entamoeba histolytica	aldose reductase, putative	0.0283	0.3016	1
Plasmodium falciparum	aldo-keto reductase, putative	0.0082	0.0462	1
Plasmodium vivax	aldehyde reductase, putative	0.0082	0.0462	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0283	0.3016	0.301
Giardia lamblia	Aldose reductase	0.0283	0.3016	0.5
Brugia malayi	glutamate-cysteine ligase modifier subunit	0.0082	0.0462	0.153
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0283	0.3016	0.301
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0283	0.3016	0.301
Trichomonas vaginalis	aldo/keto reductase, putative	0.0283	0.3016	1
Onchocerca volvulus		0.0283	0.3016	1
Schistosoma mansoni	pol-related	0.0283	0.3016	0.293
Leishmania major	prostaglandin f synthase, putative	0.0283	0.3016	1
Mycobacterium tuberculosis	Probable reductase	0.0104	0.0743	0.2464
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0104	0.0743	0.2464
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0055	0.0121	0.0402
Toxoplasma gondii	aldose reductase, putative	0.0283	0.3016	1
Trichomonas vaginalis	dihydrodiol dehydrogenase, putative	0.0283	0.3016	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0283	0.3016	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0283	0.3016	1
Trichomonas vaginalis	aldo/keto reductase, putative	0.0283	0.3016	1
Entamoeba histolytica	aldose reductase, putative	0.0283	0.3016	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0283	0.3016	1
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0055	0.0121	0.0402
Echinococcus multilocularis	aldo keto reductase	0.0283	0.3016	0.301
Brugia malayi	oxidoreductase, aldo/keto reductase family protein	0.0283	0.3016	1
Loa Loa (eye worm)	oxidoreductase	0.0283	0.3016	1
Echinococcus granulosus	aldo keto reductase	0.0283	0.3016	0.301
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0283	0.3016	0.301
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0116	0.0891	0.168
Trichomonas vaginalis	aldo-keto reductase, putative	0.0283	0.3016	1
Echinococcus multilocularis	aldo keto reductase	0.0283	0.3016	0.301
Schistosoma mansoni	aldo-keto reductase	0.0283	0.3016	0.293
Toxoplasma gondii	oxidoreductase, aldo/keto reductase family protein	0.0082	0.0462	0.153
Loa Loa (eye worm)	hypothetical protein	0.0283	0.3016	1
Trypanosoma brucei	aldo/keto reductase, putative	0.0082	0.0462	0.153
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0055	0.0121	0.0114
Loa Loa (eye worm)	oxidoreductase	0.0283	0.3016	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0283	0.3016	1
Leishmania major	aldo/keto reductase, putative,aldo/keto reductase family-like protein	0.0082	0.0462	0.153
Leishmania major	prostaglandin f2-alpha synthase/D-arabinose dehydrogenase	0.0283	0.3016	1
Echinococcus multilocularis	aldo keto reductase	0.0283	0.3016	0.301
Brugia malayi	oxidoreductase, aldo/keto reductase family protein	0.0283	0.3016	1
Mycobacterium leprae	PROBABLE NADH DEHYDROGENASE NDH	0.0104	0.0743	0.1102
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0283	0.3016	0.301
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0283	0.3016	0.301
Onchocerca volvulus		0.0283	0.3016	1
Toxoplasma gondii	aldo-keto reductase	0.0082	0.0462	0.153
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0055	0.0121	0.0114
Echinococcus multilocularis	microtubule associated protein 2	0.0833	1	1
Brugia malayi	oxidoreductase, aldo/keto reductase family protein	0.0283	0.3016	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0055	0.0121	0.0114
Trichomonas vaginalis	aldo-keto reductase, putative	0.0283	0.3016	1
Mycobacterium tuberculosis	Conserved protein	0.0082	0.0462	0.153
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0283	0.3016	0.301
Onchocerca volvulus		0.0283	0.3016	1
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0104	0.0743	0.2464
Onchocerca volvulus		0.0283	0.3016	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0283	0.3016	0.301
Echinococcus granulosus	hypothetical protein	0.0283	0.3016	0.301
Giardia lamblia	Aldose reductase	0.0283	0.3016	0.5
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0283	0.3016	0.301
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0283	0.3016	0.301
Leishmania major	aldehyde reductase, putative,oxidoreductase, putative	0.0283	0.3016	1
Echinococcus granulosus	aldo keto reductase	0.0283	0.3016	0.301
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0283	0.3016	0.301
Trypanosoma cruzi	aldo-keto reductase	0.0283	0.3016	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0283	0.3016	0.301
Trypanosoma brucei	prostaglandin f synthase	0.0283	0.3016	1
Plasmodium vivax	oxidoreductase, aldo/keto reductase domain containing protein	0.0082	0.0462	1
Echinococcus granulosus	aldo keto reductase family 1, member B4	0.0082	0.0462	0.0454
Echinococcus granulosus	aldo keto reductase	0.0283	0.3016	0.301
Loa Loa (eye worm)	oxidoreductase	0.0283	0.3016	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0283	0.3016	0.301
Mycobacterium ulcerans	oxidoreductase	0.0283	0.3016	1
Toxoplasma gondii	aldo/keto reductase family oxidoreductase	0.0082	0.0462	0.153
Leishmania major	aldo-keto reductase-like protein	0.0283	0.3016	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0283	0.3016	1
Plasmodium falciparum	aldehyde reductase, putative	0.0082	0.0462	1
Trypanosoma cruzi	aldo/keto reductase, putative	0.0082	0.0462	0.153
Trichomonas vaginalis	aldo-keto reductase, putative	0.0283	0.3016	1
Onchocerca volvulus		0.0283	0.3016	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0283	0.3016	1
Loa Loa (eye worm)	oxidoreductase	0.0283	0.3016	1
Schistosoma mansoni	microtubule-associated protein tau	0.0833	1	1
Trichomonas vaginalis	dihydrodiol dehydrogenase, putative	0.0283	0.3016	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0283	0.3016	1
Onchocerca volvulus		0.0283	0.3016	1
Mycobacterium leprae	PROBABLE OXIDOREDUCTASE	0.0283	0.3016	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0283	0.3016	0.301
Echinococcus multilocularis	aldehyde reductase	0.0201	0.1974	0.1968
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0116	0.0891	0.2953
Loa Loa (eye worm)	glutamate-cysteine ligase modifier subunit	0.0082	0.0462	0.153
Echinococcus multilocularis	voltage gated potassium channel subunit	0.0082	0.0462	0.0454
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0104	0.0743	0.2464
Echinococcus granulosus	voltage gated potassium channel subunit	0.0082	0.0462	0.0454
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0055	0.0121	0.0114
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0116	0.0891	0.2953
Loa Loa (eye worm)	oxidoreductase	0.0283	0.3016	1
Mycobacterium tuberculosis	Probable oxidoreductase	0.0283	0.3016	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0283	0.3016	0.301
Echinococcus multilocularis	aldo keto reductase	0.0283	0.3016	0.301
Brugia malayi	oxidoreductase, aldo/keto reductase family protein	0.0283	0.3016	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0283	0.3016	1
Mycobacterium tuberculosis	Probable oxidoreductase	0.0116	0.0891	0.2953
Trichomonas vaginalis	dihydrodiol dehydrogenase, putative	0.0283	0.3016	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0283	0.3016	0.301
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0104	0.0743	0.2464
Trypanosoma brucei	aldo-keto reductase, putative	0.0283	0.3016	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0283	0.3016	0.301
Brugia malayi	NADH-dependent xylose reductase	0.0082	0.0462	0.153
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0283	0.3016	0.301
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0283	0.3016	0.301
Entamoeba histolytica	aldose reductase, putative	0.0283	0.3016	1
Mycobacterium leprae	Conserved hypothetical protein	0.0201	0.1974	0.5922
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0283	0.3016	0.301
Schistosoma mansoni	aldo-keto reductase	0.0283	0.3016	0.293
Schistosoma mansoni	potassium channel beta	0.0082	0.0462	0.0344
Trichomonas vaginalis	aldo/keto reductase, putative	0.0283	0.3016	1

Activities

Activity type	Activity value	Assay description	Source	Reference
Potency (functional)	= 0.1413 um	PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)]	ChEMBL.	No reference
Potency (functional)	= 8.9125 um	PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ]	ChEMBL.	No reference
Potency (functional)	11.2202 uM	PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory)	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1558291

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1428536