Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.1043 | 0 | 0.5 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.1646 | 0.5562 | 0.5 |
Chlamydia trachomatis | methionine aminopeptidase | 0.1043 | 0 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.1646 | 0.5562 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.1646 | 0.5562 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.1646 | 0.5562 | 0.5 |
Schistosoma mansoni | microtubule-associated protein tau | 0.2127 | 1 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.1646 | 0.5562 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.1043 | 0 | 0.5 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.2127 | 1 | 1 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.1646 | 0.5562 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.1043 | 0 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.1646 | 0.5562 | 0.5 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.1646 | 0.5562 | 0.5 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.1043 | 0 | 0.5 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.1646 | 0.5562 | 1 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.1043 | 0 | 0.5 |
Treponema pallidum | methionine aminopeptidase (map) | 0.1043 | 0 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.1043 | 0 | 0.5 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.1646 | 0.5562 | 0.5 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.1043 | 0 | 0.5 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.1646 | 0.5562 | 0.5562 |
Toxoplasma gondii | methionine aminopeptidase | 0.1646 | 0.5562 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 87 % | Inhibition of recombinant HIV1 protease at 10 uM by HPLC method | ChEMBL. | 20138769 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.