Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Animal haem peroxidase family protein | 0.0209 | 0.7801 | 0.7801 |
Brugia malayi | MH2 domain containing protein | 0.0131 | 0.4605 | 0.4605 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0078 | 0.2467 | 0.2467 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.2467 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.2467 | 0.3086 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Echinococcus granulosus | jun protein | 0.0263 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0209 | 0.7801 | 0.0432 |
Brugia malayi | Animal haem peroxidase family protein | 0.0209 | 0.7801 | 0.7801 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0209 | 0.7801 | 0.7804 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0209 | 0.7801 | 0.7804 |
Schistosoma mansoni | hypothetical protein | 0.0185 | 0.683 | 0.8543 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0078 | 0.2467 | 0.3086 |
Brugia malayi | Animal haem peroxidase family protein | 0.0209 | 0.7801 | 0.7801 |
Brugia malayi | Pax transcription factor protein 2 | 0.0263 | 0.9997 | 0.9997 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0131 | 0.4605 | 0.4606 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Brugia malayi | hypothetical protein | 0.0209 | 0.7801 | 0.7801 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Echinococcus granulosus | peroxidasin | 0.0209 | 0.7801 | 0.7801 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0418 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0209 | 0.7801 | 0.0432 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.2467 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0131 | 0.4605 | 0.4606 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0418 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0209 | 0.7801 | 0.7801 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0418 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.0209 | 0.7801 | 0.0432 |
Brugia malayi | hypothetical protein | 0.0078 | 0.2467 | 0.2467 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Onchocerca volvulus | Peroxidasin homolog | 0.0209 | 0.7801 | 0.0432 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0418 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0418 | 1 |
Onchocerca volvulus | 0.0209 | 0.7801 | 0.0432 | |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Schistosoma mansoni | jun-related protein | 0.0214 | 0.7995 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0209 | 0.7801 | 0.7804 |
Schistosoma mansoni | peroxidasin | 0.0209 | 0.7801 | 0.9757 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0418 | 0.0418 |
Echinococcus multilocularis | jun protein | 0.0263 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.2467 | 0.5 |
Loa Loa (eye worm) | pax transcription factor protein 2 | 0.0263 | 0.9997 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0256 | 0.9707 | 0.971 |
Echinococcus granulosus | geminin | 0.0185 | 0.683 | 0.683 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0418 | 1 |
Schistosoma mansoni | peroxidasin | 0.0209 | 0.7801 | 0.9757 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Onchocerca volvulus | 0.0209 | 0.7801 | 0.0432 | |
Onchocerca volvulus | 0.0263 | 0.9997 | 1 | |
Echinococcus multilocularis | peroxidasin | 0.0209 | 0.7801 | 0.7801 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0078 | 0.2467 | 0.2467 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0418 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.2467 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0209 | 0.7801 | 0.0432 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0209 | 0.7801 | 0.7804 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0263 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0209 | 0.7801 | 0.7804 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0209 | 0.7801 | 0.0432 |
Schistosoma mansoni | hypothetical protein | 0.0214 | 0.7995 | 1 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0017 | 0 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0209 | 0.7801 | 0.7801 |
Brugia malayi | Blistered cuticle protein 3 | 0.0209 | 0.7801 | 0.7801 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0418 | 0.0418 |
Brugia malayi | Peroxidasin | 0.0209 | 0.7801 | 0.7801 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0418 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0185 | 0.683 | 0.8543 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Echinococcus multilocularis | geminin | 0.0185 | 0.683 | 0.683 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0263 | 1 | 1 |
Onchocerca volvulus | 0.0209 | 0.7801 | 0.0432 | |
Brugia malayi | hypothetical protein | 0.0207 | 0.7702 | 0.7702 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.7801 | 0.7804 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.