Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | p25-alpha family protein | 0.0026 | 0.0099 | 1 |
Giardia lamblia | Hypothetical protein | 0.0026 | 0.0099 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0036 | 0.0228 | 0.1008 |
Trypanosoma cruzi | p25-alpha, putative | 0.0026 | 0.0099 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0097 | 0.1012 | 0.1012 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0099 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0097 | 0.1012 | 0.1012 |
Echinococcus granulosus | geminin | 0.0193 | 0.2259 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.1012 | 0.4479 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.126 | 0.126 |
Schistosoma mansoni | hypothetical protein | 0.0077 | 0.0762 | 0.3371 |
Trypanosoma brucei | p25-alpha, putative | 0.0026 | 0.0099 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0097 | 0.1012 | 0.4479 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0228 | 0.1008 |
Treponema pallidum | ATP-binding protein (ylxH-1) | 0.0428 | 0.5286 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0097 | 0.1012 | 0.4479 |
Echinococcus granulosus | GPCR family 2 | 0.0036 | 0.0228 | 0.1008 |
Echinococcus multilocularis | tubulin polymerization promoting protein family | 0.0026 | 0.0099 | 0.0439 |
Schistosoma mansoni | p25-alpha domain containing protein | 0.0026 | 0.0099 | 0.0439 |
Echinococcus multilocularis | GPCR, family 2 | 0.0036 | 0.0228 | 0.1008 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0036 | 0.0228 | 0.1008 |
Echinococcus granulosus | tubulin polymerization promoting protein family | 0.0026 | 0.0099 | 0.0439 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0036 | 0.0228 | 0.1008 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.4211 | 0.4211 |
Echinococcus multilocularis | tubulin polymerization promoting protein family | 0.0026 | 0.0099 | 0.0439 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0113 | 0.1222 | 0.1222 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0228 | 0.0228 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0099 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0193 | 0.2259 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.1222 | 0.1222 |
Echinococcus multilocularis | geminin | 0.0193 | 0.2259 | 1 |
Toxoplasma gondii | p25-alpha family protein | 0.0026 | 0.0099 | 1 |
Onchocerca volvulus | TPPP family protein homolog | 0.0795 | 1 | 1 |
Echinococcus granulosus | tubulin polymerization promoting protein family | 0.0026 | 0.0099 | 0.0439 |
Brugia malayi | hypothetical protein | 0.0345 | 0.4211 | 0.4211 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0036 | 0.0228 | 0.0228 |
Schistosoma mansoni | P25 alpha-related | 0.0026 | 0.0099 | 0.0439 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.126 | 0.126 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0113 | 0.1222 | 0.1222 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0762 | 0.0762 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0036 | 0.0228 | 0.0228 |
Toxoplasma gondii | hypothetical protein | 0.0026 | 0.0099 | 1 |
Echinococcus multilocularis | tubulin polymerization promoting protein family | 0.0026 | 0.0099 | 0.0439 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0036 | 0.0228 | 0.0228 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0228 | 0.1008 |
Trypanosoma cruzi | p25-alpha, putative | 0.0026 | 0.0099 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.1012 | 0.4479 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0077 | 0.0762 | 0.0762 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0228 | 0.1008 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0097 | 0.1012 | 0.4479 |
Schistosoma mansoni | hypothetical protein | 0.0026 | 0.0099 | 0.0439 |
Loa Loa (eye worm) | p25-alpha family protein | 0.0795 | 1 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0036 | 0.0228 | 0.1008 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0097 | 0.1012 | 0.4479 |
Echinococcus multilocularis | tubulin polymerization promoting protein family | 0.0026 | 0.0099 | 0.0439 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.126 | 0.126 |
Plasmodium falciparum | p25-alpha family protein, putative | 0.0026 | 0.0099 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.1012 | 0.4479 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0018 | 0 | 0.5 |
Echinococcus granulosus | tubulin polymerization promoting protein family | 0.0026 | 0.0099 | 0.0439 |
Echinococcus granulosus | tubulin polymerization promoting protein family | 0.0026 | 0.0099 | 0.0439 |
Plasmodium vivax | p25-alpha family protein, putative | 0.0026 | 0.0099 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0228 | 0.1008 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0113 | 0.1222 | 0.1222 |
Schistosoma mansoni | hypothetical protein | 0.0193 | 0.2259 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.