Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0277 | 0.1285 | 0.1261 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0173 | 0.0749 | 0.0749 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0838 | 0.4176 | 1 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0173 | 0.0749 | 0.5 |
Echinococcus granulosus | prolyl endopeptidase | 0.0173 | 0.0749 | 0.0749 |
Echinococcus multilocularis | acylamino acid releasing enzyme | 0.0173 | 0.0749 | 0.0749 |
Plasmodium vivax | hypothetical protein, conserved | 0.0173 | 0.0749 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0173 | 0.0749 | 0.0723 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0173 | 0.0749 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0173 | 0.0749 | 0.5 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0033 | 0.0028 | 0.0016 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0838 | 0.4176 | 1 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0173 | 0.0749 | 0.5 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0041 | 0.0067 | 0.0067 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0173 | 0.0749 | 0.5 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0838 | 0.4176 | 0.4176 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0838 | 0.4176 | 0.417 |
Loa Loa (eye worm) | hypothetical protein | 0.0173 | 0.0749 | 0.0723 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0173 | 0.0749 | 0.5 |
Brugia malayi | hypothetical protein | 0.0561 | 0.2748 | 0.274 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0041 | 0.0067 | 0.0067 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0173 | 0.0749 | 0.0738 |
Schistosoma mansoni | acylaminoacyl-peptidase (S09 family) | 0.0173 | 0.0749 | 0.0749 |
Loa Loa (eye worm) | hypothetical protein | 0.0561 | 0.2748 | 0.2728 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0838 | 0.4176 | 1 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0734 | 0.364 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0067 | 0.004 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0838 | 0.4176 | 0.4176 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.1969 | 1 | 1 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0838 | 0.4176 | 0.4176 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.1969 | 1 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0838 | 0.4176 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0173 | 0.0749 | 0.0749 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0173 | 0.0749 | 0.5 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0173 | 0.0749 | 0.5 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0173 | 0.0749 | 0.0749 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0173 | 0.0749 | 0.0723 |
Plasmodium falciparum | peptidase, putative | 0.0173 | 0.0749 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0173 | 0.0749 | 0.5 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0038 | 0.0051 | 0.0051 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0173 | 0.0749 | 0.5 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.1969 | 1 | 1 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.1969 | 1 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0173 | 0.0749 | 0.0738 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0173 | 0.0749 | 0.0749 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0173 | 0.0749 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0173 | 0.0749 | 0.0738 |
Echinococcus granulosus | acylamino acid releasing enzyme | 0.0173 | 0.0749 | 0.0749 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0173 | 0.0749 | 0.5 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0838 | 0.4176 | 1 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0173 | 0.0749 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.1969 | 1 | 1 |
Mycobacterium tuberculosis | Probable peptidase | 0.0173 | 0.0749 | 0.5 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0173 | 0.0749 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.