Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | RE15519p | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Brugia malayi | Dopamine receptor protein 2 | 0.0035 | 0 | 0.5 |
Brugia malayi | ORL1-like opioid receptor | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | G-protein coupled receptor | 0.0035 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | Melatonin receptor type 1A | 0.0035 | 0 | 0.5 |
Toxoplasma gondii | sortilin, putative | 0.0067 | 1 | 0.5 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Loa Loa (eye worm) | TYRA-2 protein | 0.0035 | 0 | 0.5 |
Plasmodium vivax | sortilin, putative | 0.0067 | 1 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0035 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | Serotonin receptor | 0.0035 | 0 | 0.5 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | G protein-coupled receptor | 0.0035 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | putative neuropeptide receptor | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Brugia malayi | follicle stimulating hormone receptor | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Schistosoma mansoni | sortilin | 0.0048 | 0.3913 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0035 | 0 | 0.5 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | sortilin | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Plasmodium falciparum | sortilin | 0.0067 | 1 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Brugia malayi | sulfakinin receptor protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | AKH receptor | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0035 | 0 | 0.5 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0035 | 0 | 0.5 |
Brugia malayi | larval opioid receptor | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Brugia malayi | Dopamine receptor | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0035 | 0 | 0.5 |
Brugia malayi | neuropeptide F receptor | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | G-protein coupled receptor | 0.0035 | 0 | 0.5 |
Brugia malayi | GnHR receptor homolog | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | Dopamine receptor protein 1 | 0.0035 | 0 | 0.5 |
Brugia malayi | Serotonin receptor | 0.0035 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0 | 0.5 |
Brugia malayi | neuropeptide F receptor | 0.0035 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.