Detailed information for compound 1478991

Basic information

Technical information
  • TDR Targets ID: 1478991
  • Name: 3-(4-ethylphenyl)-5,6-dihydroimidazo[2,1-b][1 ,3]thiazole
  • MW: 230.329 | Formula: C13H14N2S
  • H donors: 0 H acceptors: 0 LogP: 2.56 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccc(cc1)c1csc2=NCCn12
  • InChi: 1S/C13H14N2S/c1-2-10-3-5-11(6-4-10)12-9-16-13-14-7-8-15(12)13/h3-6,9H,2,7-8H2,1H3
  • InChiKey: CRRGGHOSEGZRAM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(4-ethylphenyl)-5,6-dihydroimidazo[2,1-b]thiazole
  • STOCK2S-24622
  • ZINC00509238

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0005 0.0079 0.0079
Echinococcus granulosus stromal interaction molecule 1 0.002 0.0757 0.0758
Schistosoma mansoni hypothetical protein 0.0005 0.0079 0.0066
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0005 0.0079 0.0079
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0005 0.0079 0.0071
Echinococcus granulosus poly adp ribose polymerase 2 0.0033 0.1307 0.1309
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0005 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0005 0.0079 0.008
Trichomonas vaginalis 2-5A-dependent ribonuclease, putative 0.0003 0.0013 0.0097
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0005 0.0079 0.0071
Echinococcus multilocularis somatostatin receptor 0.0005 0.0079 0.0079
Schistosoma mansoni hypothetical protein 0.0005 0.0079 0.0066
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus multilocularis stromal interaction molecule 1 0.002 0.0757 0.0758
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0005 0.0079 0.0079
Echinococcus granulosus allatostatin A receptor 0.0005 0.0079 0.0079
Echinococcus multilocularis neuropeptide receptor A26 0.0005 0.0079 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.1307 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Schistosoma mansoni amine GPCR 0.0005 0.0079 0.0066
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0005 0.0079 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0079 0.0066
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0005 0.0079 0.0066
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Schistosoma mansoni neuropeptide receptor 0.0005 0.0079 0.0066
Plasmodium vivax tyrosine kinase-like protein, putative 0.002 0.0757 0.5
Echinococcus granulosus sex peptide receptor 0.0005 0.0079 0.0079
Schistosoma mansoni biogenic amine (5HT) receptor 0.0005 0.0079 0.0066
Brugia malayi AKH receptor 0.0005 0.0079 0.008
Schistosoma mansoni amine GPCR 0.0005 0.0079 0.0066
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Schistosoma mansoni amine GPCR 0.0005 0.0079 0.0066
Echinococcus granulosus Sterile alpha motif SAM 0.002 0.0757 0.0758
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0003 0.0013 0.0013
Giardia lamblia Kinase, NEK 0.0003 0.0013 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0005 0.0079 0.0066
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.1307 1
Entamoeba histolytica hypothetical protein 0.0033 0.1307 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.1307 1
Schistosoma mansoni opsin-like receptor 0.0005 0.0079 0.0066
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus granulosus neuropeptide receptor 0.0005 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0005 0.0079 0.0071
Entamoeba histolytica hypothetical protein 0.0033 0.1307 0.5
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0005 0.0079 0.0079
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0033 0.1307 0.5
Schistosoma mansoni opsin-like receptor 0.0005 0.0079 0.0066
Echinococcus multilocularis allatostatin A receptor 0.0005 0.0079 0.0079
Schistosoma mansoni lar interacting protein (lip)-related protein 0.002 0.0757 0.0745
Echinococcus multilocularis g protein coupled receptor 0.0005 0.0079 0.0079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Brugia malayi Dopamine receptor protein 1 0.0005 0.0079 0.008
Trichomonas vaginalis ankyrin, putative 0.0003 0.0013 0.0097
Plasmodium falciparum tyrosine kinase-like protein 0.002 0.0757 0.5
Echinococcus multilocularis sterile alpha and tir motif containing protein 0.002 0.0757 0.0758
Brugia malayi GnHR receptor homolog 0.0005 0.0079 0.008
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Brugia malayi G protein-coupled receptor 0.0005 0.0079 0.008
Schistosoma mansoni lip-related protein (liprin) alpha 0.002 0.0757 0.0745
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0005 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Brugia malayi Patatin-like phospholipase family protein 0.0003 0.0013 0.0013
Echinococcus multilocularis fmrfamide receptor 0.0005 0.0079 0.0079
Echinococcus granulosus biogenic amine 5HT receptor 0.0005 0.0079 0.0079
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0003 0.0013 0.0097
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus multilocularis g-protein coupled receptor 0.0005 0.0079 0.0079
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0005 0.0079 0.0066
Loa Loa (eye worm) hypothetical protein 0.002 0.0757 0.0817
Schistosoma mansoni growth hormone secretagogue receptor 0.0005 0.0079 0.0066
Loa Loa (eye worm) hypothetical protein 0.002 0.0757 0.0817
Schistosoma mansoni hypothetical protein 0.0005 0.0079 0.0066
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0005 0.0079 0.0066
Brugia malayi sulfakinin receptor protein 0.0005 0.0079 0.008
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus multilocularis dro:myosuppressin receptor 0.0005 0.0079 0.0079
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0003 0.0013 0.0097
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0005 0.0079 0.008
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus granulosus peptide allatostatin:somatostatin 0.0005 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0003 0.0013 0.0097
Schistosoma mansoni biogenic amine (5HT) receptor 0.0005 0.0079 0.0066
Schistosoma mansoni adenoreceptor 0.0005 0.0079 0.0066
Trichomonas vaginalis c2h2 zinc finger protein, putative 0.002 0.0757 0.5791
Loa Loa (eye worm) TYRA-2 protein 0.0005 0.0079 0.0071
Loa Loa (eye worm) neuropeptide F receptor 0.0005 0.0079 0.0071
Echinococcus granulosus g protein coupled receptor 0.0005 0.0079 0.0079
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0005 0.0079 0.0079
Echinococcus multilocularis neuropeptide receptor 0.0005 0.0079 0.0079
Echinococcus multilocularis neuropeptide Y receptor 0.0005 0.0079 0.0079
Echinococcus granulosus tm gpcr rhodopsin 0.0005 0.0079 0.0079
Brugia malayi G protein-coupled receptor F59B2.13 0.0005 0.0079 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0033 0.1307 0.1309
Brugia malayi Dopamine receptor protein 2 0.0005 0.0079 0.008
Echinococcus granulosus tankyrase 0.0228 0.9986 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0757 0.5791
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0033 0.1307 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0757 0.0817
Brugia malayi hypothetical protein 0.0005 0.0079 0.008
Echinococcus granulosus neuropeptide receptor A26 0.0005 0.0079 0.0079
Schistosoma mansoni neuropeptide receptor 0.0005 0.0079 0.0066
Brugia malayi sterile alpha and TIR motif containing protein 1 isoform a 0.002 0.0757 0.0768
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0005 0.0079 0.0066
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0003 0.0013 0.0097
Echinococcus granulosus sterile alpha and tir motif containing protein 0.002 0.0757 0.0758
Schistosoma mansoni histamine h1 receptor 0.0005 0.0079 0.0066
Echinococcus multilocularis G-protein coupled receptor, putative 0.0005 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0005 0.0079 0.0079
Brugia malayi hypothetical protein 0.0005 0.0079 0.008
Echinococcus granulosus hypothetical protein 0.0005 0.0079 0.0079
Echinococcus multilocularis g protein coupled receptor 0.0005 0.0079 0.0079
Echinococcus multilocularis neuropeptide receptor 0.0005 0.0079 0.0079
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0005 0.0079 0.0066
Brugia malayi neuropeptide F receptor 0.0005 0.0079 0.008
Brugia malayi hypothetical protein 0.0005 0.0079 0.008
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Brugia malayi ORL1-like opioid receptor 0.0005 0.0079 0.008
Brugia malayi hypothetical protein 0.002 0.0757 0.0768
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0005 0.0079 0.008
Echinococcus granulosus g-protein coupled receptor 0.0005 0.0079 0.0079
Echinococcus multilocularis G protein coupled receptor 139 0.0005 0.0079 0.0079
Echinococcus multilocularis neuropeptide s receptor 0.0005 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus multilocularis fmrfamide receptor 0.0005 0.0079 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0079 0.0066
Echinococcus granulosus g protein coupled receptor 0.0005 0.0079 0.0079
Echinococcus granulosus neuropeptides capa receptor 0.0005 0.0079 0.0079
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0005 0.0079 0.0071
Brugia malayi hypothetical protein 0.0005 0.0079 0.008
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0003 0.0013 0.0097
Echinococcus granulosus liprin alpha 2 0.002 0.0757 0.0758
Loa Loa (eye worm) G-protein coupled receptor 0.0005 0.0079 0.0071
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0005 0.0079 0.0079
Schistosoma mansoni alpha-1 adrenergic receptor 0.0005 0.0079 0.0066
Plasmodium falciparum protein kinase, putative 0.002 0.0757 0.5
Echinococcus granulosus g protein coupled receptor 0.0005 0.0079 0.0079
Brugia malayi WGR domain containing protein 0.0033 0.1307 0.1325
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0005 0.0079 0.0066
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0005 0.0079 0.0079
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0005 0.0079 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.1307 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0005 0.0079 0.0079
Echinococcus granulosus Ankyrin 0.0003 0.0013 0.0013
Echinococcus granulosus SAM domain containing protein 0.002 0.0757 0.0758
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0033 0.1307 0.1309
Echinococcus granulosus tm gpcr rhodopsin 0.0005 0.0079 0.0079
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0003 0.0013 0.0097
Schistosoma mansoni biogenic amine receptor 0.0005 0.0079 0.0066
Schistosoma mansoni biogenic amine receptor 0.0005 0.0079 0.0066
Schistosoma mansoni biogenic amine receptor 0.0005 0.0079 0.0066
Echinococcus granulosus alpha 1A adrenergic receptor 0.0005 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Trichomonas vaginalis protein phosphatase 1 regulatory subunit 12C, putative 0.0003 0.0013 0.0097
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Schistosoma mansoni neuropeptide receptor 0.0005 0.0079 0.0066
Echinococcus granulosus liprin beta 1 0.002 0.0757 0.0758
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0005 0.0079 0.0066
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0003 0.0013 0.0097
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0033 0.1307 0.1296
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0005 0.0079 0.0071
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0005 0.0079 0.008
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0005 0.0079 0.0066
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Loa Loa (eye worm) toll and interleukin 1 receptor domain-containing protein isoform f 0.002 0.0757 0.0817
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0005 0.0079 0.0079
Entamoeba histolytica zinc finger protein, putative 0.0033 0.1307 0.5
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus multilocularis neuropeptides capa receptor 0.0005 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus granulosus tm gpcr rhodopsin 0.0005 0.0079 0.0079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0079 0.0066
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus granulosus fmrfamide receptor 0.0005 0.0079 0.0079
Onchocerca volvulus 0.002 0.0757 0.0765
Schistosoma mansoni neuropeptide F-like receptor 0.0005 0.0079 0.0066
Echinococcus granulosus neuropeptide FF receptor 2 0.0005 0.0079 0.0079
Brugia malayi larval opioid receptor 0.0005 0.0079 0.008
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0003 0.0014 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0079 0.0066
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0003 0.0013 0.0013
Echinococcus granulosus 7TM GPCR rhodopsin 0.0005 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Brugia malayi hypothetical protein 0.0005 0.0079 0.008
Echinococcus multilocularis neuropeptides capa receptor 0.0005 0.0079 0.0079
Schistosoma mansoni amine GPCR 0.0005 0.0079 0.0066
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0003 0.0013 0.0097
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0005 0.0079 0.0066
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0005 0.0079 0.0079
Echinococcus multilocularis orexin receptor type 2 0.0005 0.0079 0.0079
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0033 0.1307 1
Leishmania major huntingtin interacting protein (HIP), putative 0.0003 0.0013 0.5
Echinococcus multilocularis neuropeptide Y receptor 0.0005 0.0079 0.0079
Brugia malayi Tachykinin-like peptides receptor 99D 0.0005 0.0079 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Schistosoma mansoni myosin xvIII 0.0005 0.0079 0.0066
Echinococcus multilocularis liprin alpha 2 0.002 0.0757 0.0758
Echinococcus multilocularis serotonin receptor 0.0005 0.0079 0.0079
Trichomonas vaginalis unc-44 ankyrins, putative 0.0003 0.0013 0.0097
Loa Loa (eye worm) hypothetical protein 0.002 0.0757 0.0817
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Loa Loa (eye worm) G-protein coupled receptor 0.0005 0.0079 0.0071
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0005 0.0079 0.0079
Echinococcus granulosus biogenic amine 5HT receptor 0.0005 0.0079 0.0079
Echinococcus multilocularis Ankyrin 0.0003 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.002 0.0757 0.0745
Brugia malayi coiled-coil like protein 1 0.002 0.0757 0.0768
Schistosoma mansoni hypothetical protein 0.002 0.0757 0.0745
Brugia malayi hypothetical protein 0.0005 0.0079 0.008
Giardia lamblia Kinase, NEK 0.0003 0.0013 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0079 0.0066
Entamoeba histolytica hypothetical protein 0.0033 0.1307 0.5
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus granulosus neuropeptide Y receptor 0.0005 0.0079 0.0079
Echinococcus multilocularis sex peptide receptor 0.0005 0.0079 0.0079
Brugia malayi putative neuropeptide receptor 0.0005 0.0079 0.008
Brugia malayi follicle stimulating hormone receptor 0.0005 0.0079 0.008
Loa Loa (eye worm) hypothetical protein 0.002 0.0757 0.0817
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0005 0.0079 0.0066
Schistosoma mansoni amine GPCR 0.0005 0.0079 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.1307 1
Echinococcus granulosus poly ADP ribose polymerase 1 0.0033 0.1307 0.1309
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0005 0.0079 0.0066
Echinococcus multilocularis liprin beta 1 0.002 0.0757 0.0758
Brugia malayi Liprin-alpha 2 0.002 0.0757 0.0768
Brugia malayi Neurabin protein 1 0.002 0.0757 0.0768
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0005 0.0079 0.0079
Brugia malayi Serotonin receptor 0.0005 0.0079 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Echinococcus granulosus 7tm_1 domain containing protein 0.0005 0.0079 0.0079
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0003 0.0013 0.0097
Loa Loa (eye worm) hypothetical protein 0.0172 0.7519 0.8257
Brugia malayi G-protein coupled receptor 0.0005 0.0079 0.008
Brugia malayi hypothetical protein 0.002 0.0757 0.0768
Echinococcus granulosus tachykinin peptides receptor 99D 0.0005 0.0079 0.0079
Schistosoma mansoni hypothetical protein 0.002 0.0757 0.0745
Schistosoma mansoni neuropeptide receptor 0.0005 0.0079 0.0066
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0033 0.1307 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0005 0.0079 0.0079
Echinococcus multilocularis SAM domain containing protein 0.002 0.0757 0.0758
Echinococcus granulosus neuropeptide Y receptor 0.0005 0.0079 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0757 0.5791
Schistosoma mansoni opsin-like receptor 0.0005 0.0079 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.1307 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus multilocularis serotonin receptor 0.0005 0.0079 0.0079
Echinococcus granulosus neuropeptides capa receptor 0.0005 0.0079 0.0079
Schistosoma mansoni sarm1 0.002 0.0757 0.0745
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0757 0.5791
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Schistosoma mansoni neuropeptide f receptor 76f 0.0005 0.0079 0.0066
Trichomonas vaginalis ankyrin, putative 0.0003 0.0014 0.0109
Loa Loa (eye worm) neuropeptide F receptor 0.0005 0.0079 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.1307 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0003 0.0014 0.0109
Brugia malayi RE15519p 0.0005 0.0079 0.008
Trypanosoma brucei poly(adp-ribose) polymerase 0.0033 0.1307 1
Echinococcus granulosus neuropeptide receptor 0.0005 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Brugia malayi hypothetical protein 0.0005 0.0079 0.008
Brugia malayi hypothetical protein 0.0005 0.0079 0.008
Brugia malayi WGR domain containing protein 0.0033 0.1307 0.1325
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0005 0.0079 0.0079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0005 0.0079 0.0066
Echinococcus granulosus serotonin receptor 0.0005 0.0079 0.0079
Loa Loa (eye worm) melatonin receptor type 1A 0.0005 0.0079 0.0071
Brugia malayi Melatonin receptor type 1A 0.0005 0.0079 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.1307 1
Brugia malayi Serotonin receptor 0.0005 0.0079 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0079 0.0066
Trichomonas vaginalis unc-44 ankyrins, putative 0.0003 0.0013 0.0097
Echinococcus granulosus G protein coupled receptor 139 0.0005 0.0079 0.0079
Echinococcus multilocularis tankyrase 0.0228 0.9986 1
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.1307 1
Brugia malayi Dopamine receptor 0.0005 0.0079 0.008
Onchocerca volvulus 0.002 0.0757 0.0765
Loa Loa (eye worm) tnks protein 0.0208 0.9103 1
Echinococcus granulosus orexin receptor type 2 0.0005 0.0079 0.0079
Entamoeba histolytica hypothetical protein 0.0033 0.1307 0.5
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0033 0.1307 0.1309
Brugia malayi Tnks protein 0.0225 0.9861 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0003 0.0013 0.0097
Schistosoma mansoni hypothetical protein 0.002 0.0757 0.0745
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Loa Loa (eye worm) hypothetical protein 0.0033 0.1307 0.1423
Brugia malayi hypothetical protein 0.0005 0.0079 0.008
Onchocerca volvulus Tankyrase homolog 0.0205 0.8951 1
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0033 0.1307 0.1423
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0757 0.5791
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0079 0.0066
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0005 0.0079 0.0079
Trichomonas vaginalis ion channel nompc, putative 0.0003 0.0013 0.0097
Echinococcus granulosus somatostatin receptor 0.0005 0.0079 0.0079
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0033 0.1307 0.1296
Brugia malayi hypothetical protein 0.0005 0.0079 0.008
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Loa Loa (eye worm) hypothetical protein 0.0005 0.0079 0.0071
Echinococcus multilocularis g protein coupled receptor 0.0005 0.0079 0.0079
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0005 0.0079 0.0079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Echinococcus granulosus neuropeptide s receptor 0.0005 0.0079 0.0079
Schistosoma mansoni neuropeptide F-like receptor 0.0005 0.0079 0.0066
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0003 0.0013 0.0097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0079 0.0066
Echinococcus granulosus dro:myosuppressin receptor 0.0005 0.0079 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0079 0.0079
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0005 0.0079 0.0079
Brugia malayi putative neuropeptide receptor NPR1 0.0005 0.0079 0.008
Brugia malayi G-protein coupled receptor 0.0005 0.0079 0.008
Brugia malayi neuropeptide F receptor 0.0005 0.0079 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0079 0.0066
Schistosoma mansoni hypothetical protein 0.0005 0.0079 0.0066
Trichomonas vaginalis multiple ankyrin repeats single kh domain protein, putative 0.0003 0.0013 0.0097

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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