Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | angiogenesis inhibito | 0.0054 | 0.1242 | 0.1388 |
Trichomonas vaginalis | set domain proteins, putative | 0.0235 | 1 | 0.5 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0207 | 0.8618 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.7172 | 0.8312 |
Echinococcus granulosus | adam | 0.0051 | 0.1071 | 0.4885 |
Echinococcus multilocularis | a disintegrin and metalloproteinase with | 0.0074 | 0.2191 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1071 | 0.1188 |
Brugia malayi | ADAMTS-like protease | 0.0054 | 0.1242 | 0.1388 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0053 | 0.5 |
Brugia malayi | hypothetical protein | 0.0051 | 0.1071 | 0.1188 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1319 | 0.1478 |
Schistosoma mansoni | adam (A disintegrin and metalloprotease | 0.0051 | 0.1071 | 0.4759 |
Onchocerca volvulus | Papilin homolog | 0.0056 | 0.1319 | 0.1273 |
Echinococcus multilocularis | adam | 0.0051 | 0.1071 | 0.4759 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0053 | 0.0241 |
Brugia malayi | Pre-SET motif family protein | 0.0207 | 0.8618 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0053 | 0.5 |
Schistosoma mansoni | ADAMTS5 peptidase (M12 family) | 0.0074 | 0.2191 | 1 |
Echinococcus granulosus | a disintegrin and metalloproteinase with | 0.0074 | 0.2191 | 1 |
Brugia malayi | ADAM-TS Spacer 1 family protein | 0.0177 | 0.7172 | 0.8312 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.