Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | glutamate receptor | 0.0208 | 0.2358 | 0.2358 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0103 | 0.0539 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.6682 | 0.6682 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0103 | 0.0539 | 0.0297 |
Brugia malayi | angiogenesis inhibito | 0.0141 | 0.1196 | 0.1238 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0602 | 0.9142 | 1 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0136 | 0.1108 | 0.1108 |
Brugia malayi | hypothetical protein | 0.0132 | 0.1037 | 0.1031 |
Echinococcus granulosus | a disintegrin and metalloproteinase with | 0.0192 | 0.2074 | 0.1871 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0443 | 0.6411 | 0.6319 |
Loa Loa (eye worm) | hypothetical protein | 0.0651 | 1 | 1 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0443 | 0.6411 | 0.6319 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0529 | 0.7892 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0103 | 0.0539 | 0.0539 |
Schistosoma mansoni | adam (A disintegrin and metalloprotease | 0.0132 | 0.1037 | 0.0886 |
Trypanosoma brucei | RNA helicase, putative | 0.0469 | 0.6852 | 0.5 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0136 | 0.1108 | 0.1108 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0103 | 0.0539 | 0.0325 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0258 | 0.3216 | 0.3335 |
Loa Loa (eye worm) | glutamate receptor | 0.0529 | 0.7892 | 0.7892 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0103 | 0.0539 | 0.0325 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0136 | 0.1108 | 0.1122 |
Echinococcus multilocularis | a disintegrin and metalloproteinase with | 0.0192 | 0.2074 | 0.1871 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.1267 | 0.1267 |
Onchocerca volvulus | Papilin homolog | 0.0145 | 0.1267 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0103 | 0.0539 | 0.0378 |
Schistosoma mansoni | ADAMTS5 peptidase (M12 family) | 0.0192 | 0.2074 | 0.2052 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0258 | 0.3216 | 0.3881 |
Echinococcus granulosus | adam | 0.0132 | 0.1037 | 0.0808 |
Brugia malayi | ADAM-TS Spacer 1 family protein | 0.0459 | 0.6682 | 0.8417 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0651 | 1 | 1 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0479 | 0.7034 | 0.8878 |
Echinococcus multilocularis | adam | 0.0132 | 0.1037 | 0.0808 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0103 | 0.0539 | 0.0325 |
Brugia malayi | ADAMTS-like protease | 0.0141 | 0.1196 | 0.1238 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0103 | 0.0539 | 0.0297 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0103 | 0.0539 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.1037 | 0.1037 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0443 | 0.6411 | 0.6929 |
Schistosoma mansoni | hypothetical protein | 0.0469 | 0.6852 | 0.7424 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.1108 | 0.1108 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.025 | 0.025 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.