Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0476 | 0.193 | 0.193 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0622 | 0.2791 | 1 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.1851 | 1 | 1 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0147 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable peptidase | 0.0147 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0147 | 0 | 0.5 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.1851 | 1 | 1 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0147 | 0 | 0.5 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0622 | 0.2791 | 1 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.1851 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0147 | 0 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0622 | 0.2791 | 1 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.1851 | 1 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0622 | 0.2791 | 0.2791 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0147 | 0 | 0.5 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0622 | 0.2791 | 0.2791 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0147 | 0 | 0.5 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0147 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0476 | 0.193 | 0.193 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0147 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0147 | 0 | 0.5 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0147 | 0 | 0.5 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0622 | 0.2791 | 0.2791 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0147 | 0 | 0.5 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0622 | 0.2791 | 1 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0147 | 0 | 0.5 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0147 | 0 | 0.5 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.1851 | 1 | 1 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0622 | 0.2791 | 0.2791 |
Plasmodium falciparum | peptidase, putative | 0.0147 | 0 | 0.5 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0622 | 0.2791 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0147 | 0 | 0.5 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0622 | 0.2791 | 1 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0147 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.