Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | carbonic anhydrase, putative | 0.1411 | 0.9475 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0461 | 0.1849 | 0.5 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.0759 | 0.4239 | 0.7358 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1477 | 1 | 0.5 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.1011 | 0.6263 | 0.5788 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.1011 | 0.6263 | 0.5788 |
Plasmodium falciparum | carbonic anhydrase | 0.0461 | 0.1849 | 0.5 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1011 | 0.6263 | 1 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.0948 | 0.5761 | 1 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.1011 | 0.6263 | 0.5 |
Schistosoma mansoni | carbonic anhydrase | 0.1411 | 0.9475 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1037 | 0.6473 | 1 |
Echinococcus multilocularis | carbonic anhydrase II | 0.1011 | 0.6263 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.1011 | 0.6263 | 0.5 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.1011 | 0.6263 | 1 |
Echinococcus granulosus | carbonic anhydrase II | 0.1011 | 0.6263 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.1011 | 0.6263 | 0.9545 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.1011 | 0.6263 | 0.5 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.1011 | 0.6263 | 0.9545 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1477 | 1 | 0.5 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.0883 | 0.5237 | 0.9089 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.1411 | 0.9475 | 1 |
Leishmania major | carbonic anhydrase family protein, putative | 0.1411 | 0.9475 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.