Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | voltage gated potassium channel | 0.0076 | 0.0211 | 0.1145 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0063 | 0.0092 | 0.5 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0063 | 0.0092 | 0.045 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0264 | 0.184 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0076 | 0.0211 | 0.1028 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0092 | 0.0092 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0264 | 0.184 | 0.184 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0063 | 0.0092 | 0.0092 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0076 | 0.0211 | 0.1145 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0211 | 0.0211 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0063 | 0.0092 | 0.0502 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0246 | 0.1689 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0092 | 0.0092 |
Onchocerca volvulus | 0.0063 | 0.0092 | 0.5 | |
Schistosoma mansoni | voltage-gated potassium channel | 0.0288 | 0.2051 | 1 |
Toxoplasma gondii | hypothetical protein | 0.1202 | 1 | 0.5 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0264 | 0.184 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1202 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1537 | 0.1537 |
Echinococcus granulosus | voltage gated potassium channel | 0.0076 | 0.0211 | 0.1145 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0264 | 0.184 | 1 |
Echinococcus granulosus | serotonin transporter | 0.0063 | 0.0092 | 0.0502 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0076 | 0.0211 | 0.1145 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0288 | 0.2051 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0076 | 0.0211 | 0.1028 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0246 | 0.1689 | 1 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0063 | 0.0092 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0092 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.1202 | 1 | 1 |
Echinococcus multilocularis | serotonin transporter | 0.0063 | 0.0092 | 0.0502 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0076 | 0.0211 | 0.1145 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0063 | 0.0092 | 0.045 |
Loa Loa (eye worm) | inward rectifying k channel family protein 1 | 0.1202 | 1 | 1 |
Loa Loa (eye worm) | serotonin transporter b | 0.0063 | 0.0092 | 0.0092 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.