Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.332 | 0 | 0.5 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.8806 | 1 | 0.5 |
Schistosoma mansoni | alpha-l-fucosidase | 0.7569 | 0.7745 | 0.5 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.332 | 0 | 0.5 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.7569 | 0.7745 | 0.5 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.8806 | 1 | 0.5 |
Brugia malayi | Alpha-L-fucosidase family protein | 0.7569 | 0.7745 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 70.7946 uM | PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] | ChEMBL. | No reference |
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.