Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Protein kinase domain containing protein | 0.0903 | 0.2176 | 0.5877 |
Echinococcus granulosus | hypothetical protein | 0.0601 | 0.0752 | 0.0752 |
Leishmania major | protein kinase, putative | 0.0615 | 0.0818 | 0.3757 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0979 | 0.2533 | 0.2533 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0615 | 0.0818 | 0.3757 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0903 | 0.2176 | 0.2176 |
Echinococcus multilocularis | dual specificity | 0.0903 | 0.2176 | 0.2176 |
Loa Loa (eye worm) | CMGC/CLK protein kinase | 0.0615 | 0.0818 | 0.0818 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0615 | 0.0818 | 0.0818 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0615 | 0.0818 | 0.3757 |
Plasmodium vivax | serine/threonine kinase-1, putative | 0.0615 | 0.0818 | 1 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0903 | 0.2176 | 1 |
Echinococcus multilocularis | 0.0601 | 0.0752 | 0.0752 | |
Entamoeba histolytica | protein kinase, putative | 0.0903 | 0.2176 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0615 | 0.0818 | 0.2208 |
Loa Loa (eye worm) | hypothetical protein | 0.1228 | 0.3703 | 0.3703 |
Leishmania major | protein kinase, putative | 0.0615 | 0.0818 | 0.3757 |
Trypanosoma brucei | kinetoplastid kinetochore protein 10 | 0.0615 | 0.0818 | 0.3757 |
Plasmodium falciparum | protein serine/threonine kinase-1 | 0.0615 | 0.0818 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.089 | 0.2111 | 0.2111 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0903 | 0.2176 | 1 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0903 | 0.2176 | 1 |
Brugia malayi | hypothetical protein | 0.1228 | 0.3703 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0903 | 0.2176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0601 | 0.0752 | 0.0752 |
Echinococcus granulosus | dual specificity protein kinase clk2 | 0.0615 | 0.0818 | 0.0818 |
Toxoplasma gondii | cell-cycle-associated protein kinase CLK, putative | 0.0615 | 0.0818 | 1 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0615 | 0.0818 | 0.3757 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0615 | 0.0818 | 1 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0903 | 0.2176 | 0.2176 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0903 | 0.2176 | 1 |
Trypanosoma brucei | kinetoplastid kinetochore protein 19 | 0.0615 | 0.0818 | 0.3757 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0903 | 0.2176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.089 | 0.2111 | 0.2111 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0615 | 0.0818 | 0.0818 |
Entamoeba histolytica | hypothetical protein | 0.0903 | 0.2176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1228 | 0.3703 | 0.3703 |
Echinococcus granulosus | dual specificity | 0.0903 | 0.2176 | 0.2176 |
Giardia lamblia | Kinase, CMGC CLK | 0.0615 | 0.0818 | 1 |
Echinococcus multilocularis | dual specificity protein kinase clk2 | 0.0615 | 0.0818 | 0.0818 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0615 | 0.0818 | 0.3757 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.