Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | p21 activated protein kinase 1 Dpak1 | 0.0458 | 0.1325 | 0.1628 |
Trichomonas vaginalis | STE family protein kinase | 0.0458 | 0.1325 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0458 | 0.1325 | 1 |
Giardia lamblia | Kinase, STE STE20 | 0.0458 | 0.1325 | 0.5 |
Entamoeba histolytica | p21-activated kinase | 0.0458 | 0.1325 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0458 | 0.1325 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0452 | 0.1288 | 0.1288 |
Trichomonas vaginalis | STE family protein kinase | 0.0458 | 0.1325 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0458 | 0.1325 | 0.1628 |
Echinococcus granulosus | p21 activated protein kinase 1 Dpak1 | 0.0458 | 0.1325 | 0.1628 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0458 | 0.1325 | 0.1628 |
Schistosoma mansoni | protein kinase | 0.0273 | 0.0037 | 0.0277 |
Schistosoma mansoni | protein kinase | 0.0458 | 0.1325 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0458 | 0.1325 | 0.1628 |
Schistosoma mansoni | protein kinase | 0.0458 | 0.1325 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0273 | 0.0037 | 0.0277 |
Brugia malayi | Protein kinase domain | 0.0458 | 0.1325 | 0.1325 |
Entamoeba histolytica | protein kinase, putative | 0.0273 | 0.0037 | 0.0277 |
Echinococcus multilocularis | PAK box P21 Rho binding | 0.0273 | 0.0037 | 0.0045 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0452 | 0.1288 | 0.9715 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 4 | 0.1436 | 0.8137 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0273 | 0.0037 | 0.0277 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0458 | 0.1325 | 0.1628 |
Entamoeba histolytica | protein kinase, putative | 0.0458 | 0.1325 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PAK 4 | 0.1436 | 0.8137 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.