Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0552 | 0.4372 | 0.4372 |
Entamoeba histolytica | protein kinase, putative | 0.0366 | 0.0139 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0552 | 0.4372 | 0.4293 |
Loa Loa (eye worm) | hypothetical protein | 0.0383 | 0.0531 | 0.0531 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0558 | 0.451 | 0.5 |
Plasmodium falciparum | protein serine/threonine kinase-1 | 0.0558 | 0.451 | 0.5 |
Leishmania major | protein kinase, putative | 0.0558 | 0.451 | 1 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0558 | 0.451 | 1 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0366 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0383 | 0.0531 | 0.0531 |
Echinococcus multilocularis | dual specificity protein kinase clk2 | 0.0558 | 0.451 | 0.4433 |
Trypanosoma brucei | kinetoplastid kinetochore protein 19 | 0.0558 | 0.451 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0558 | 0.451 | 0.4433 |
Brugia malayi | hypothetical protein | 0.0383 | 0.0531 | 0.0898 |
Echinococcus granulosus | dual specificity protein kinase clk2 | 0.0558 | 0.451 | 0.4433 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0558 | 0.451 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0366 | 0.0139 | 0.5 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0558 | 0.451 | 1 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0558 | 0.451 | 1 |
Leishmania major | protein kinase, putative | 0.0558 | 0.451 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase CLK, putative | 0.0558 | 0.451 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0366 | 0.0139 | 0.5 |
Trypanosoma brucei | kinetoplastid kinetochore protein 10 | 0.0558 | 0.451 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0558 | 0.451 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0366 | 0.0139 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0558 | 0.451 | 0.4433 |
Giardia lamblia | Kinase, CMGC CLK | 0.0558 | 0.451 | 0.5 |
Echinococcus multilocularis | 0.0552 | 0.4372 | 0.4293 | |
Loa Loa (eye worm) | CMGC/CLK protein kinase | 0.0558 | 0.451 | 0.451 |
Plasmodium vivax | serine/threonine kinase-1, putative | 0.0558 | 0.451 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.