Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | jun proto-oncogene | Starlite/ChEMBL | References |
Homo sapiens | mitogen-activated protein kinase 10 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | jun protein | 0.0101 | 0.3253 | 0.2808 |
Mycobacterium leprae | Probable lipase LipE | 0.0032 | 0.0619 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0032 | 0.0619 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0032 | 0.0619 | 0.5 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0032 | 0.0619 | 0.0619 |
Echinococcus multilocularis | muscleblind protein | 0.0134 | 0.4503 | 0.4141 |
Schistosoma mansoni | jun-related protein | 0.0082 | 0.2528 | 0.2035 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0027 | 0.0401 | 0.0401 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0619 | 0.0619 |
Brugia malayi | Cytochrome P450 family protein | 0.0027 | 0.0401 | 0.0401 |
Echinococcus multilocularis | jun protein | 0.0101 | 0.3253 | 0.2808 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0032 | 0.0619 | 1 |
Brugia malayi | bZIP transcription factor family protein | 0.0101 | 0.3253 | 0.3253 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0032 | 0.0619 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0032 | 0.0619 | 0.0619 |
Brugia malayi | hypothetical protein | 0.008 | 0.2422 | 0.2422 |
Leishmania major | hypothetical protein, conserved | 0.0032 | 0.0619 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0619 | 0.0619 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0032 | 0.0619 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.0032 | 0.0619 | 0.0619 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0619 | 0.0619 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0208 | 0.7321 | 0.7321 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0619 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0032 | 0.0619 | 0.5 |
Mycobacterium ulcerans | lipase LipD | 0.0032 | 0.0619 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0032 | 0.0619 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0619 | 0.0619 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0619 | 0.0619 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0619 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0207 | 0.7267 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0032 | 0.0619 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0032 | 0.0619 | 0.0619 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0032 | 0.0619 | 0.5 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0032 | 0.0619 | 0.0619 |
Echinococcus granulosus | muscleblind protein | 0.0134 | 0.4503 | 0.4141 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0032 | 0.0619 | 1 |
Onchocerca volvulus | 0.008 | 0.2422 | 1 | |
Brugia malayi | beta-lactamase | 0.0032 | 0.0619 | 0.0619 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0032 | 0.0619 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0101 | 0.3253 | 0.2808 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0619 | 0.0619 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0101 | 0.3253 | 0.2808 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0032 | 0.0619 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.3147 | 0.3147 |
Brugia malayi | Muscleblind-like protein | 0.0134 | 0.4503 | 0.4503 |
Mycobacterium ulcerans | beta-lactamase | 0.0032 | 0.0619 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0032 | 0.0619 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.2528 | 0.2035 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.4503 | 0.4503 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.4503 | 0.4503 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0134 | 0.4503 | 0.4141 |
Brugia malayi | follicle stimulating hormone receptor | 0.0208 | 0.7321 | 0.7321 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.