Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Plasmodium vivax | hexose transporter | 0.0117 | 1 | 0.5 |
Trypanosoma brucei | glucose transporter 1E | 0.0036 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Schistosoma mansoni | glucose transport protein | 0.0117 | 1 | 0.5 |
Loa Loa (eye worm) | sugar transporter | 0.0117 | 1 | 0.5 |
Leishmania major | glucose transporter, lmgt1 | 0.0036 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0117 | 1 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0117 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0117 | 1 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Leishmania major | glucose transporter, lmgt2 | 0.0036 | 0 | 0.5 |
Leishmania major | glucose transporter, lmgt3 | 0.0036 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0117 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0117 | 1 | 1 |
Trypanosoma cruzi | hexose transporter, putative | 0.0036 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0036 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0117 | 1 | 1 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.0036 | 0 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0036 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Plasmodium falciparum | hexose transporter | 0.0117 | 1 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter 2A | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Trypanosoma cruzi | hexose transporter | 0.0036 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 13.1154 uM | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] | ChEMBL. | No reference |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Plasmodium falciparum | ChEMBL23 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.