Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.265 | 0.3334 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0113 | 0.0103 | 0.0103 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.7881 | 1 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0625 | 0.0754 | 0.0754 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.265 | 0.3334 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0625 | 0.0754 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0625 | 0.0754 | 0.0754 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0625 | 0.0754 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0124 | 0.0116 | 0.0116 |
Echinococcus granulosus | acylamino acid releasing enzyme | 0.0625 | 0.0754 | 0.0754 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0625 | 0.0754 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0625 | 0.0754 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0625 | 0.0754 | 0.0754 |
Loa Loa (eye worm) | hypothetical protein | 0.0625 | 0.0754 | 0.0754 |
Loa Loa (eye worm) | hypothetical protein | 0.2025 | 0.2538 | 0.2538 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0084 | 0.0084 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0625 | 0.0754 | 0.5 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0625 | 0.0754 | 0.5 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0625 | 0.0754 | 0.5 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.0391 | 0.0457 | 0.0457 |
Schistosoma mansoni | acylaminoacyl-peptidase (S09 family) | 0.0625 | 0.0754 | 0.0754 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.265 | 0.3334 | 0.3334 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0625 | 0.0754 | 0.0754 |
Brugia malayi | hypothetical protein | 0.2025 | 0.2538 | 0.2538 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0625 | 0.0754 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.7881 | 1 | 1 |
Echinococcus granulosus | prolyl endopeptidase | 0.0625 | 0.0754 | 0.0754 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0625 | 0.0754 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0625 | 0.0754 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.265 | 0.3334 | 1 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.265 | 0.3334 | 0.3334 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.7881 | 1 | 1 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0625 | 0.0754 | 0.5 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.7881 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0625 | 0.0754 | 0.0754 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0625 | 0.0754 | 0.5 |
Mycobacterium tuberculosis | Probable peptidase | 0.0625 | 0.0754 | 0.5 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0625 | 0.0754 | 0.5 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.0391 | 0.0457 | 0.0457 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.265 | 0.3334 | 0.3334 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0625 | 0.0754 | 0.0754 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0625 | 0.0754 | 0.0754 |
Plasmodium falciparum | peptidase, putative | 0.0625 | 0.0754 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0625 | 0.0754 | 0.0754 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.265 | 0.3334 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.265 | 0.3334 | 0.3334 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0113 | 0.0103 | 0.0103 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0625 | 0.0754 | 0.0754 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0113 | 0.0103 | 0.0103 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.265 | 0.3334 | 1 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0625 | 0.0754 | 0.5 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.0391 | 0.0457 | 0.0457 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0625 | 0.0754 | 0.5 |
Echinococcus multilocularis | acylamino acid releasing enzyme | 0.0625 | 0.0754 | 0.0754 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0113 | 0.0103 | 0.0103 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0625 | 0.0754 | 0.0754 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.265 | 0.3334 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0124 | 0.0116 | 0.0116 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.7881 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.