Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | SNF1-related protein kinase regulatory subunit beta, putative | 0.0065 | 0.1267 | 1 |
Echinococcus granulosus | serine:threonine kinase SAD 1 | 0.0052 | 0.0734 | 0.0734 |
Brugia malayi | loechrig isoform VII | 0.013 | 0.3992 | 0.3537 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Loa Loa (eye worm) | CAMK/CAMKL/BRSK protein kinase | 0.0052 | 0.0734 | 0.0032 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Echinococcus multilocularis | AMPK beta subunit | 0.0065 | 0.1267 | 0.1267 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0052 | 0.0734 | 0.0734 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Giardia lamblia | 5-AMP-activated protein kinase, beta-1 subunit | 0.0065 | 0.1267 | 0.1635 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0065 | 0.1267 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Echinococcus multilocularis | serine:threonine kinase SAD 1 | 0.0052 | 0.0734 | 0.0734 |
Loa Loa (eye worm) | 5'-AMP-activated protein kinase | 0.0065 | 0.1267 | 0.0605 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Echinococcus granulosus | 5' AMP activated protein kinase subunit gamma | 0.013 | 0.3992 | 0.3992 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Echinococcus granulosus | AMPK beta subunit | 0.0065 | 0.1267 | 0.1267 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0052 | 0.0734 | 0.0734 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0734 | 0.0032 |
Trypanosoma cruzi | 5'-AMP-activated protein kinase subunit beta, putative | 0.0065 | 0.1267 | 1 |
Schistosoma mansoni | protein kinase subunit gamma | 0.013 | 0.3992 | 0.3992 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Trypanosoma brucei | 5'-AMP-activated protein kinase subunit beta | 0.0065 | 0.1267 | 1 |
Echinococcus granulosus | 5' AMP activated protein kinase catalytic | 0.0273 | 1 | 1 |
Echinococcus multilocularis | 5' AMP activated protein kinase subunit gamma | 0.013 | 0.3992 | 0.3992 |
Loa Loa (eye worm) | loechrig isoform VII | 0.013 | 0.3992 | 0.3537 |
Echinococcus multilocularis | 5' AMP activated protein kinase catalytic | 0.0273 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Toxoplasma gondii | histone kinase SNF1, putative | 0.0052 | 0.0734 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0273 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0052 | 0.0734 | 0.0734 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0052 | 0.0734 | 0.0734 |
Brugia malayi | 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein | 0.0065 | 0.1267 | 0.0605 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0052 | 0.0734 | 0.5 |
Brugia malayi | 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein | 0.0065 | 0.1267 | 0.0605 |
Loa Loa (eye worm) | CAMK/CAMKL/AMPK protein kinase | 0.0273 | 1 | 1 |
Plasmodium falciparum | serine/threonine protein kinase KIN | 0.0052 | 0.0734 | 0.5 |
Brugia malayi | putative serine/threonine kinase SADA gamma | 0.0052 | 0.0734 | 0.0032 |
Onchocerca volvulus | Alicorn homolog | 0.0057 | 0.0921 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Echinococcus multilocularis | 5' AMP activated protein kinase subunit gamma | 0.0122 | 0.3654 | 0.3654 |
Schistosoma mansoni | protein kinase subunit beta | 0.0065 | 0.1267 | 0.1267 |
Plasmodium vivax | serine/threonine protein kinase KIN, putative | 0.0052 | 0.0734 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0052 | 0.0734 | 0.5 |
Giardia lamblia | 5-AMP-activated protein kinase, gamma-1 subunit | 0.013 | 0.3992 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 100 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.