Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (functional) | > 200 ug ml-1 | The concentration required to reduce cell growth by 50% was measured on Human Embryonic Lung (HEL) cells | ChEMBL. | 10197958 |
CC50 (functional) | > 200 ug ml-1 | The concentration required to reduce 50% cell viability on CEM cells of Human T-lymphocyte | ChEMBL. | 10197958 |
CC50 (functional) | > 200 ug ml-1 | The concentration required to reduce cell growth by 50% was measured on Human Embryonic Lung (HEL) cells | ChEMBL. | 10197958 |
CC50 (functional) | > 200 ug ml-1 | The concentration required to reduce 50% cell viability on CEM cells of Human T-lymphocyte | ChEMBL. | 10197958 |
EC50 (functional) | > 200 ug ml-1 | Concentration of the required to protect CEM cells of Human T-lymphocyte against Cytopathogenicity of HIV-1(III-B) by 50% | ChEMBL. | 10197958 |
EC50 (functional) | > 200 ug ml-1 | Concentration of the required to protect CEM cells of Human T-lymphocyte against Cytopathogenicity of HIV-2 by 50% | ChEMBL. | 10197958 |
IC50 (functional) | > 50 ug ml-1 | The concentration required to reduce virus plaque formation by 50% was measured on AD-169 strains of human cytomegalovirus | ChEMBL. | 10197958 |
IC50 (functional) | > 50 ug ml-1 | The concentration required to reduce virus plaque formation by 50% was measured on Davis strains of human cytomegalovirus | ChEMBL. | 10197958 |
IC50 (functional) | > 50 ug ml-1 | The concentration required to reduce virus plaque formation by 50% was measured on OKA strain of VZV expressing viral thymidine kinase(TK+) | ChEMBL. | 10197958 |
IC50 (functional) | > 50 ug ml-1 | The concentration required to reduce virus plaque formation by 50% was measured on YS strain of VZV expressing viral thymidine kinase(TK+) | ChEMBL. | 10197958 |
IC50 (functional) | > 50 ug ml-1 | The concentration required to reduce virus plaque formation by 50% was measured on 07/1 strain of VZV expressing viral thymidine kinase(TK-) | ChEMBL. | 10197958 |
IC50 (functional) | > 50 ug ml-1 | The concentration required to reduce virus plaque formation by 50% was measured on YS/Rstrain of VZV expressing viral thymidine kinase(TK-) | ChEMBL. | 10197958 |
MCC (functional) | > 50 ug ml-1 | The minimum cytotoxic concentration was measured on Human Embryonic Lung (HEL) cells | ChEMBL. | 10197958 |
MCC (functional) | > 50 ug ml-1 | The minimum cytotoxic concentration was measured on Human Embryonic Lung (HEL) cells | ChEMBL. | 10197958 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.