Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | geminin | 0.0335 | 0.9639 | 0.9639 |
Echinococcus multilocularis | solute carrier family 28 | 0.0339 | 1 | 1 |
Echinococcus granulosus | concentrative Na nucleoside cotransporter | 0.0339 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0335 | 0.9639 | 0.5 |
Echinococcus granulosus | Na+ dependent nucleoside transporter | 0.0339 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0335 | 0.9639 | 0.5 |
Echinococcus multilocularis | concentrative Na+ nucleoside cotransporter | 0.0339 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.