Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0276 | 0.2159 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.1208 | 1 | 1 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0276 | 0.2159 | 0.2069 |
Plasmodium vivax | protein kinase Crk2 | 0.0276 | 0.2159 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1208 | 1 | 1 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0276 | 0.2159 | 0.2069 |
Trichomonas vaginalis | cyclins, putative | 0.0032 | 0.0113 | 0.0086 |
Echinococcus granulosus | cyclin dependent kinase | 0.0276 | 0.2159 | 0.2069 |
Giardia lamblia | Kinase, CMGC CDK | 0.0276 | 0.2159 | 0.2069 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.1208 | 1 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.0276 | 0.2159 | 0.2069 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.1208 | 1 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.1208 | 1 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.1208 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0032 | 0.0113 | 0.0086 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0276 | 0.2159 | 0.2069 |
Echinococcus granulosus | mitogen activated protein kinase | 0.1208 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0276 | 0.2159 | 0.2137 |
Plasmodium falciparum | protein kinase 5 | 0.0276 | 0.2159 | 0.5 |
Trichomonas vaginalis | cyclin A, putative | 0.0032 | 0.0113 | 0.0086 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0276 | 0.2159 | 0.2137 |
Trypanosoma brucei | protein kinase, putative | 0.1208 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0113 | 0.0113 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0276 | 0.2159 | 0.2069 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.1208 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0276 | 0.2159 | 0.2069 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0113 | 0.0113 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0276 | 0.2159 | 0.2069 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.1208 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0032 | 0.0113 | 0.0086 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1208 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0032 | 0.0113 | 0.0086 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0276 | 0.2159 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0276 | 0.2159 | 0.2069 |
Trichomonas vaginalis | cyclin B, putative | 0.0032 | 0.0113 | 0.0086 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0276 | 0.2159 | 0.2069 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0276 | 0.2159 | 0.2069 |
Giardia lamblia | Kinase, CMGC MAPK | 0.1208 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0276 | 0.2159 | 0.2159 |
Brugia malayi | cell division control protein 2 homolog | 0.0276 | 0.2159 | 0.2069 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0276 | 0.2159 | 0.2069 |
Trichomonas vaginalis | cyclins, putative | 0.0032 | 0.0113 | 0.0086 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0276 | 0.2159 | 0.2069 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.1208 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0276 | 0.2159 | 0.2069 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0276 | 0.2159 | 0.2159 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1208 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.1208 | 1 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.1208 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0276 | 0.2159 | 0.2069 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0276 | 0.2159 | 0.2137 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0276 | 0.2159 | 0.2069 |
Loa Loa (eye worm) | hypothetical protein | 0.0262 | 0.2043 | 0.2043 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1208 | 1 | 1 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0276 | 0.2159 | 0.2069 |
Trichomonas vaginalis | cyclin B, putative | 0.0032 | 0.0113 | 0.0086 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0276 | 0.2159 | 0.2069 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1208 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1208 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0276 | 0.2159 | 0.2159 |
Onchocerca volvulus | 0.0032 | 0.0113 | 0.5 | |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0276 | 0.2159 | 0.2069 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1208 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0032 | 0.0113 | 0.0086 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0276 | 0.2159 | 0.2069 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.