Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | dual specificity serine/threonine tyrosine kinase | 0.0396 | 0.3628 | 1 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.018 | 0.1334 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0396 | 0.3628 | 1 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.018 | 0.1334 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.018 | 0.1334 | 0.5 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.018 | 0.1334 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.018 | 0.1334 | 0.1334 |
Brugia malayi | serine/threonine protein kinase 6 | 0.018 | 0.1334 | 0.1334 |
Loa Loa (eye worm) | TTK protein kinase | 0.0396 | 0.3628 | 0.3628 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.018 | 0.1334 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0054 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0997 | 1 | 1 |
Onchocerca volvulus | Dual specificity protein kinase TTK homolog | 0.0396 | 0.3628 | 1 |
Brugia malayi | hypothetical protein | 0.007 | 0.0166 | 0.0166 |
Trichomonas vaginalis | AGC family protein kinase | 0.018 | 0.1334 | 0.3375 |
Loa Loa (eye worm) | AUR protein kinase | 0.018 | 0.1334 | 0.1334 |
Brugia malayi | Protein kinase domain containing protein | 0.0396 | 0.3628 | 0.3628 |
Trypanosoma cruzi | aurora B kinase, putative | 0.018 | 0.1334 | 1 |
Entamoeba histolytica | protein kinase , putative | 0.018 | 0.1334 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.018 | 0.1334 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0166 | 0.0166 |
Entamoeba histolytica | protein kinase, putative | 0.018 | 0.1334 | 0.5 |
Toxoplasma gondii | aurora kinase | 0.018 | 0.1334 | 1 |
Brugia malayi | serine/threonine kinase 12 | 0.018 | 0.1334 | 0.1334 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.018 | 0.1334 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.018 | 0.1334 | 0.3375 |
Trichomonas vaginalis | AGC family protein kinase | 0.018 | 0.1334 | 0.3375 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0396 | 0.3628 | 1 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.018 | 0.1334 | 0.1334 |
Trypanosoma brucei | aurora B kinase | 0.018 | 0.1334 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.018 | 0.1334 | 0.3375 |
Giardia lamblia | Kinase, TTK | 0.0396 | 0.3628 | 1 |
Echinococcus multilocularis | dual specificity serine:threonine tyrosine | 0.0396 | 0.3628 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.018 | 0.1334 | 0.1334 |
Leishmania major | protein kinase, putative | 0.018 | 0.1334 | 1 |
Echinococcus granulosus | dual specificity serine:threonine tyrosine | 0.0396 | 0.3628 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.