Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | NIMA-related protein kinase NIMA1 | 0.0142 | 0.1208 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0131 | 0.1071 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0055 | 0.0127 | 0.0127 |
Plasmodium falciparum | NIMA related kinase 1 | 0.0142 | 0.1208 | 1 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase I | 0.0475 | 0.5334 | 0.9996 |
Giardia lamblia | Kinase, NEK | 0.0142 | 0.1208 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0475 | 0.5336 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0852 | 1 | 1 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase I | 0.0475 | 0.5334 | 0.9996 |
Echinococcus granulosus | serine:threonine protein kinase Chk2 | 0.0475 | 0.5336 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0475 | 0.5336 | 0.5336 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0069 | 0.0299 | 0.2475 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0131 | 0.1071 | 0.8866 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0131 | 0.1071 | 0.1071 |
Echinococcus granulosus | dual specificity serine:threonine tyrosine | 0.0055 | 0.0127 | 0.0239 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0131 | 0.1071 | 0.8866 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0131 | 0.1071 | 0.8866 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0131 | 0.1071 | 0.2008 |
Loa Loa (eye worm) | TTK protein kinase | 0.0055 | 0.0127 | 0.0127 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0131 | 0.1071 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0069 | 0.0299 | 0.2475 |
Loa Loa (eye worm) | CAMK/CAMKL/CHK1 protein kinase | 0.0852 | 1 | 1 |
Giardia lamblia | Kinase, NEK | 0.0142 | 0.1208 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0131 | 0.1071 | 0.8866 |
Giardia lamblia | Kinase, TTK | 0.0055 | 0.0127 | 0.1054 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0055 | 0.0127 | 0.1054 |
Schistosoma mansoni | kinase | 0.007 | 0.0319 | 0.0319 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0131 | 0.1071 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase Chk2 | 0.0475 | 0.5336 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0131 | 0.1071 | 0.1071 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0055 | 0.0127 | 0.1054 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0131 | 0.1071 | 0.8866 |
Trichomonas vaginalis | STE family protein kinase | 0.0142 | 0.1208 | 1 |
Trypanosoma brucei | polo-like protein kinase | 0.0131 | 0.1071 | 1 |
Schistosoma mansoni | dual specificity serine/threonine tyrosine kinase | 0.0055 | 0.0127 | 0.0127 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0131 | 0.1071 | 0.2008 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0131 | 0.1071 | 0.8866 |
Echinococcus multilocularis | dual specificity serine:threonine tyrosine | 0.0055 | 0.0127 | 0.0239 |
Giardia lamblia | Kinase, PLK | 0.0131 | 0.1071 | 0.8866 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0131 | 0.1071 | 0.2008 |
Giardia lamblia | Kinase, NEK | 0.0142 | 0.1208 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0142 | 0.1208 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0131 | 0.1071 | 0.8866 |
Plasmodium vivax | NIMA-related protein kinase (Pfnek-1), putative | 0.0142 | 0.1208 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0131 | 0.1071 | 1 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0131 | 0.1071 | 0.1071 |
Entamoeba histolytica | protein kinase, putative | 0.0475 | 0.5336 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.