Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0335 | 0.1424 | 0.5 |
Schistosoma mansoni | family S10 unassigned peptidase (S10 family) | 0.1748 | 1 | 1 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0177 | 0.0467 | 0.015 |
Schistosoma mansoni | family S10 non-peptidase homologue (S10 family) | 0.1748 | 1 | 1 |
Leishmania major | serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10 | 0.1748 | 1 | 0.5 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.1748 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0245 | 0.0881 | 0.073 |
Echinococcus granulosus | poly adp ribose polymerase 2 | 0.0177 | 0.0467 | 0.0467 |
Brugia malayi | WGR domain containing protein | 0.0322 | 0.1348 | 0.0924 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.1748 | 1 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.1748 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1748 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.0467 | 0.0309 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0322 | 0.1348 | 0.106 |
Echinococcus granulosus | poly ADP ribose polymerase 1 | 0.0322 | 0.1348 | 0.1348 |
Schistosoma mansoni | lysosomal protective protein precursor (cathepsin A) (carboxypeptidase | 0.0173 | 0.0441 | 0.0123 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.1748 | 1 | 1 |
Entamoeba histolytica | poly(ADP-ribose) polymerase, putative | 0.0322 | 0.1348 | 0.5 |
Echinococcus multilocularis | lysosomal protective protein | 0.1748 | 1 | 1 |
Echinococcus granulosus | lysosomal protective protein | 0.1748 | 1 | 1 |
Onchocerca volvulus | Uncharacterized serine carboxypeptidase homolog | 0.1748 | 1 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.1748 | 1 | 1 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.1748 | 1 | 1 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.1748 | 1 | 1 |
Echinococcus granulosus | family S10 non peptidase ue S10 family | 0.1575 | 0.8952 | 0.8952 |
Echinococcus multilocularis | family S10 non peptidase ue (S10 family) | 0.1575 | 0.8952 | 0.89 |
Echinococcus multilocularis | poly (ADP ribose) polymerase 1 | 0.0322 | 0.1348 | 0.0924 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.