Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | AGC family protein kinase | 0.2238 | 1 | 0.5 |
Echinococcus multilocularis | 3 phosphoinositide dependent protein kinase 1 | 0.2238 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.2238 | 1 | 0.5 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.2238 | 1 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.2238 | 1 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2238 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.2238 | 1 | 0.5 |
Toxoplasma gondii | MAPEG family protein | 0.1036 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.2238 | 1 | 0.5 |
Echinococcus granulosus | 3-phosphoinositide-dependent protein kinase 1 | 0.2238 | 1 | 1 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.2238 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.