Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Protein kinase c protein 2 | 0.3905 | 0.8257 | 1 |
Echinococcus granulosus | NDR protein kinase | 0.0711 | 0.026 | 0.026 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0711 | 0.026 | 0.0327 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0711 | 0.026 | 0.026 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0711 | 0.026 | 0.026 |
Entamoeba histolytica | protein kinase, putative | 0.0711 | 0.026 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2245 | 0.4101 | 0.5154 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0711 | 0.026 | 0.026 |
Schistosoma mansoni | family S10 non-peptidase homologue (S10 family) | 0.2245 | 0.4101 | 0.4101 |
Loa Loa (eye worm) | hypothetical protein | 0.3282 | 0.6697 | 0.8417 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0711 | 0.026 | 0.026 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.2245 | 0.4101 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0711 | 0.026 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0711 | 0.026 | 0.5 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.2245 | 0.4101 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.2245 | 0.4101 | 1 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0711 | 0.026 | 0.0327 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.2245 | 0.4101 | 0.5 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0711 | 0.026 | 0.0327 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0711 | 0.026 | 0.0327 |
Trichomonas vaginalis | AGC family protein kinase | 0.0711 | 0.026 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0711 | 0.026 | 0.026 |
Schistosoma mansoni | serine/threonine protein kinase | 0.4601 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0711 | 0.026 | 0.026 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.1319 | 0.1782 | 0.1782 |
Trichomonas vaginalis | AGC family protein kinase | 0.0711 | 0.026 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0711 | 0.026 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0711 | 0.026 | 1 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0711 | 0.026 | 0.0327 |
Brugia malayi | Serine carboxypeptidase F41C3.5 precursor | 0.2245 | 0.4101 | 0.4803 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.2245 | 0.4101 | 1 |
Brugia malayi | protein kinase C II. | 0.1319 | 0.1782 | 0.1903 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0711 | 0.026 | 0.026 |
Trichomonas vaginalis | AGC family protein kinase | 0.0711 | 0.026 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1319 | 0.1782 | 0.1782 |
Schistosoma mansoni | serine/threonine kinase | 0.0711 | 0.026 | 0.026 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.3282 | 0.6697 | 0.6697 |
Trichomonas vaginalis | AGC family protein kinase | 0.0711 | 0.026 | 1 |
Echinococcus multilocularis | serine threonine protein kinase | 0.4098 | 0.874 | 0.874 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0711 | 0.026 | 0.026 |
Entamoeba histolytica | protein kinase, putative | 0.0711 | 0.026 | 0.5 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.3402 | 0.6997 | 0.8794 |
Schistosoma mansoni | serine/threonine protein kinase | 0.4601 | 1 | 1 |
Echinococcus multilocularis | family S10 non peptidase ue (S10 family) | 0.2023 | 0.3545 | 0.3545 |
Echinococcus multilocularis | lysosomal protective protein | 0.2245 | 0.4101 | 0.4101 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0711 | 0.026 | 0.026 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.3282 | 0.6697 | 0.6697 |
Echinococcus granulosus | lysosomal protective protein | 0.2245 | 0.4101 | 0.4101 |
Echinococcus granulosus | protein kinase c iota type | 0.1214 | 0.152 | 0.152 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0711 | 0.026 | 0.026 |
Schistosoma mansoni | atypical protein kinase C | 0.1214 | 0.152 | 0.152 |
Echinococcus granulosus | protein kinase C gamma type | 0.4098 | 0.874 | 0.874 |
Loa Loa (eye worm) | hypothetical protein | 0.0711 | 0.026 | 0.0327 |
Toxoplasma gondii | AGC kinase | 0.0711 | 0.026 | 0.5 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0711 | 0.026 | 0.0327 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.4601 | 1 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.2245 | 0.4101 | 0.5 |
Echinococcus multilocularis | protein kinase c iota type | 0.1214 | 0.152 | 0.152 |
Echinococcus granulosus | protein kinase c epsilon type | 0.1319 | 0.1782 | 0.1782 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0711 | 0.026 | 0.026 |
Trichomonas vaginalis | AGC family protein kinase | 0.0711 | 0.026 | 1 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0711 | 0.026 | 0.026 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0711 | 0.026 | 0.0327 |
Trichomonas vaginalis | AGC family protein kinase | 0.0711 | 0.026 | 1 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.2245 | 0.4101 | 0.5 |
Onchocerca volvulus | Uncharacterized serine carboxypeptidase homolog | 0.2245 | 0.4101 | 1 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.3282 | 0.6697 | 0.6697 |
Echinococcus granulosus | family S10 non peptidase ue S10 family | 0.2023 | 0.3545 | 0.3545 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0711 | 0.026 | 0.026 |
Leishmania major | serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10 | 0.2245 | 0.4101 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.3785 | 0.7957 | 1 |
Schistosoma mansoni | family S10 unassigned peptidase (S10 family) | 0.2245 | 0.4101 | 0.4101 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0711 | 0.026 | 0.026 |
Trichomonas vaginalis | AGC family protein kinase | 0.0711 | 0.026 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0711 | 0.026 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0711 | 0.026 | 1 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.1319 | 0.1782 | 0.2239 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.