Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.401 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0678 | 0 | 0.5 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.1415 | 0.2213 | 0.2213 |
Echinococcus granulosus | carboxylesterase 5A | 0.401 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0678 | 0 | 0.5 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.1415 | 0.2213 | 0.2213 |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.1415 | 0.2213 | 0.2213 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0678 | 0 | 0.5 |
Onchocerca volvulus | 0.0678 | 0 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.401 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0678 | 0 | 0.5 |
Toxoplasma gondii | MAPEG family protein | 0.1415 | 0.2213 | 0.5 |
Echinococcus granulosus | microsomal glutathione S transferase 3 | 0.1415 | 0.2213 | 0.2213 |
Onchocerca volvulus | 0.0678 | 0 | 0.5 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.401 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.401 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.401 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0678 | 0 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.401 | 1 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0678 | 0 | 0.5 |
Onchocerca volvulus | 0.0678 | 0 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.401 | 1 | 1 |
Onchocerca volvulus | 0.0678 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.401 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.401 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.401 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.401 | 1 | 1 |
Onchocerca volvulus | 0.0678 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 0 % | In vitro agonistic activity of the compound against angiotensin II in the rabbit aorta | ChEMBL. | 2913307 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.