Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | fatty acid desaturase, putative | 0.0208 | 0 | 0.5 |
Toxoplasma gondii | MAPEG family protein | 0.1921 | 1 | 0.5 |
Onchocerca volvulus | 0.0208 | 0 | 0.5 | |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.1921 | 1 | 0.5 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.1921 | 1 | 0.5 |
Onchocerca volvulus | 0.0208 | 0 | 0.5 | |
Leishmania major | fatty-acid desaturase, putative | 0.0208 | 0 | 0.5 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.1921 | 1 | 0.5 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0208 | 0 | 0.5 |
Leishmania major | stearic acid desaturase, putative | 0.0208 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.