Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | proteinase inhibitor I25 cystatin | 0.0047 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0047 | 0.5 | 0.5 | |
Onchocerca volvulus | 0.0047 | 0.5 | 0.5 | |
Onchocerca volvulus | 0.0047 | 0.5 | 0.5 | |
Onchocerca volvulus | 0.0047 | 0.5 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.5 | 0.5 |
Brugia malayi | cystatin | 0.0047 | 0.5 | 0.5 |
Loa Loa (eye worm) | cysteine protease inhibitor | 0.0047 | 0.5 | 0.5 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0047 | 0.5 | 0.5 |
Echinococcus multilocularis | proteinase inhibitor I25, cystatin | 0.0047 | 0.5 | 0.5 |
Schistosoma mansoni | cystatin B | 0.0047 | 0.5 | 0.5 |
Loa Loa (eye worm) | cystatin-type cysteine proteinase inhibitor CPI-1 | 0.0047 | 0.5 | 0.5 |
Echinococcus granulosus | Cystatin B Stefin B | 0.0047 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0047 | 0.5 | 0.5 | |
Brugia malayi | cystatin-type cysteine proteinase inhibitor CPI-2, putative | 0.0047 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.5 | 0.5 |
Echinococcus multilocularis | Cystatin B (Stefin B) | 0.0047 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0047 | 0.5 | 0.5 | |
Trichomonas vaginalis | Clan IH, family I25, phytocystatin-like peptidase inhibitor | 0.0047 | 0.5 | 0.5 |
Loa Loa (eye worm) | cystatin | 0.0047 | 0.5 | 0.5 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 22081789 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.