Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0039 | 0.1315 | 1 | |
Plasmodium falciparum | NIMA related kinase 4 | 0.0156 | 1 | 0.5 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0039 | 0.1315 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0039 | 0.1315 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Onchocerca volvulus | 0.0039 | 0.1315 | 1 | |
Brugia malayi | Cation transporter family protein | 0.0039 | 0.1315 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0039 | 0.1315 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0039 | 0.1315 | 1 |
Trypanosoma cruzi | Serine/threonine-protein kinase NEK11, putative | 0.0156 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Trypanosoma cruzi | NIMA-related kinase, putative | 0.0156 | 1 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0039 | 0.1315 | 0.1315 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0039 | 0.1315 | 0.1355 |
Trypanosoma cruzi | Serine/threonine-protein kinase NEK11, putative | 0.0156 | 1 | 1 |
Toxoplasma gondii | NEK kinase | 0.0156 | 1 | 0.5 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0039 | 0.1315 | 0.1355 |
Loa Loa (eye worm) | LGC-31 protein | 0.0039 | 0.1315 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0039 | 0.1315 | 0.1355 |
Leishmania major | protein kinase, putative | 0.0156 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Toxoplasma gondii | NEK kinase | 0.0156 | 1 | 0.5 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0039 | 0.1315 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Onchocerca volvulus | 0.0039 | 0.1315 | 1 | |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0039 | 0.1315 | 1 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0039 | 0.1315 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0039 | 0.1315 | 0.1315 |
Giardia lamblia | Kinase, NEK | 0.0156 | 1 | 0.5 |
Schistosoma mansoni | nAChR subunit | 0.0039 | 0.1315 | 0.1315 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0039 | 0.1315 | 0.1355 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0039 | 0.1315 | 1 |
Brugia malayi | Cation transporter family protein | 0.0039 | 0.1315 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0156 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0039 | 0.1315 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0039 | 0.1315 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0039 | 0.1315 | 0.1315 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0039 | 0.1315 | 0.1355 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0039 | 0.1315 | 1 |
Brugia malayi | Cation transporter family protein | 0.0039 | 0.1315 | 1 |
Trypanosoma brucei | Serine/threonine-protein kinase NEK16, putative | 0.0156 | 1 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase Nek1 | 0.0152 | 0.9707 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0039 | 0.1315 | 0.1315 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0039 | 0.1315 | 1 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0039 | 0.1315 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0039 | 0.1315 | 0.1315 |
Onchocerca volvulus | 0.0039 | 0.1315 | 1 | |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0039 | 0.1315 | 1 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0039 | 0.1315 | 0.1355 |
Schistosoma mansoni | nAChR subunit | 0.0039 | 0.1315 | 0.1315 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0039 | 0.1315 | 0.1315 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0039 | 0.1315 | 0.1315 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0039 | 0.1315 | 0.1355 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0039 | 0.1315 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0039 | 0.1315 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0156 | 1 | 0.5 |
Leishmania major | serine/threonine-protein kinase, putative | 0.0156 | 1 | 0.5 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0039 | 0.1315 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0039 | 0.1315 | 1 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0039 | 0.1315 | 0.1355 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0039 | 0.1315 | 1 |
Loa Loa (eye worm) | ACC-1 protein | 0.0039 | 0.1315 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0156 | 1 | 0.5 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0039 | 0.1315 | 1 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0039 | 0.1315 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Loa Loa (eye worm) | ACC-1 protein | 0.0039 | 0.1315 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0039 | 0.1315 | 0.1355 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0039 | 0.1315 | 0.1315 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0039 | 0.1315 | 0.1355 |
Echinococcus granulosus | nAChR subunit | 0.0039 | 0.1315 | 0.1355 |
Plasmodium vivax | serine/threonine-protein kinase NEK4, putative | 0.0156 | 1 | 0.5 |
Trypanosoma brucei | NIMA-related protein kinase | 0.0156 | 1 | 0.5 |
Trypanosoma brucei | Serine/threonine-protein kinase NEK11, putative | 0.0156 | 1 | 0.5 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0039 | 0.1315 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Onchocerca volvulus | 0.0039 | 0.1315 | 1 | |
Plasmodium vivax | serine/threonine-protein kinase Nek1, putative | 0.0156 | 1 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0156 | 1 | 0.5 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0039 | 0.1315 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0156 | 1 | 0.5 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0039 | 0.1315 | 0.1355 |
Schistosoma mansoni | nAChR subunit | 0.0039 | 0.1315 | 0.1315 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0039 | 0.1315 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0039 | 0.1315 | 0.1315 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0039 | 0.1315 | 0.1355 |
Onchocerca volvulus | Putative nachr subunit | 0.0039 | 0.1315 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0039 | 0.1315 | 0.1355 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0039 | 0.1315 | 0.1315 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0039 | 0.1315 | 0.1355 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0039 | 0.1315 | 0.1355 |
Plasmodium falciparum | NIMA related kinase 2 | 0.0156 | 1 | 0.5 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0039 | 0.1315 | 0.1355 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0039 | 0.1315 | 0.1355 |
Echinococcus granulosus | serine:threonine protein kinase Nek1 | 0.0152 | 0.9707 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0156 | 1 | 1 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0039 | 0.1315 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0039 | 0.1315 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Toxoplasma gondii | NEK kinase | 0.0156 | 1 | 0.5 |
Leishmania major | protein kinase, putative,serine/threonine-protein kinase Nek1, putative | 0.0156 | 1 | 0.5 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0039 | 0.1315 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0039 | 0.1315 | 0.1355 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0039 | 0.1315 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0039 | 0.1315 | 1 |
Onchocerca volvulus | 0.0039 | 0.1315 | 1 | |
Trypanosoma cruzi | Serine/threonine-protein kinase NEK16, putative | 0.0156 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1315 | 1 |
Echinococcus multilocularis | nAChR subunit | 0.0039 | 0.1315 | 0.1355 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0039 | 0.1315 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.