Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | semaphorin 1A | 0.0008 | 0.1165 | 0.1165 |
Echinococcus multilocularis | serine:threonine protein kinase Chk2 | 0.0042 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0004 | 0 | 0.5 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0004 | 0 | 0.5 |
Loa Loa (eye worm) | sema domain-containing protein | 0.0008 | 0.1165 | 0.2348 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0004 | 0 | 0.5 |
Brugia malayi | Plexin repeat family protein | 0.0019 | 0.4053 | 0.8169 |
Echinococcus multilocularis | hypothetical protein | 0.0008 | 0.1165 | 0.1165 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0004 | 0 | 0.5 |
Entamoeba histolytica | tyrosin kinase, putative | 0.0004 | 0.0243 | 0.0243 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0042 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0008 | 0.1165 | 0.1165 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0004 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.1165 | 0.2348 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.1165 | 0.2348 |
Brugia malayi | Sema domain containing protein | 0.0008 | 0.1165 | 0.2348 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0004 | 0 | 0.5 |
Brugia malayi | Sema domain containing protein | 0.0008 | 0.1165 | 0.2348 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.1165 | 0.2348 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0004 | 0.0243 | 0.0243 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase I | 0.0042 | 0.9996 | 0.9996 |
Entamoeba histolytica | protein kinase, putative | 0.0042 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0042 | 1 | 1 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase I | 0.0042 | 0.9996 | 0.9996 |
Brugia malayi | plexin A | 0.0023 | 0.4961 | 1 |
Loa Loa (eye worm) | plexin A | 0.0023 | 0.4961 | 1 |
Schistosoma mansoni | plexin | 0.0011 | 0.198 | 0.198 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4053 | 0.8169 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0004 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0004 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.1165 | 0.2348 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.198 | 0.198 |
Echinococcus multilocularis | plexin a4 | 0.0023 | 0.4961 | 0.4961 |
Loa Loa (eye worm) | sema domain-containing protein | 0.0008 | 0.1165 | 0.2348 |
Schistosoma mansoni | semaphorin 5-related | 0.0008 | 0.1165 | 0.1165 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.198 | 0.3991 |
Echinococcus multilocularis | semaphorin 5B | 0.0008 | 0.1165 | 0.1165 |
Schistosoma mansoni | plexin | 0.0019 | 0.4053 | 0.4053 |
Onchocerca volvulus | 0.0019 | 0.4053 | 1 | |
Brugia malayi | hypothetical protein | 0.0008 | 0.1165 | 0.2348 |
Brugia malayi | hypothetical protein | 0.0008 | 0.1165 | 0.2348 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0004 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0004 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.1165 | 0.2348 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0004 | 0 | 0.5 |
Echinococcus granulosus | semaphorin 5B | 0.0008 | 0.1165 | 0.1165 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0004 | 0 | 0.5 |
Echinococcus granulosus | plexin a4 | 0.0023 | 0.4961 | 0.4961 |
Schistosoma mansoni | hypothetical protein | 0.0008 | 0.1165 | 0.1165 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.1165 | 0.2348 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.