Detailed information for compound 1643617

Basic information

Technical information
  • TDR Targets ID: 1643617
  • Name: 3-[(Z)-heptadec-10-enyl]-5-methoxy-2-[(4-meth ylpiperazin-1-yl)methyl]cyclohexa-2,5-diene-1 ,4-dione
  • MW: 486.73 | Formula: C30H50N2O3
  • H donors: 0 H acceptors: 2 LogP: 7.87 Rotable bonds: 18
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCC/C=C\CCCCCCCCCC1=C(CN2CCN(CC2)C)C(=O)C=C(C1=O)OC
  • InChi: 1S/C30H50N2O3/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26-27(25-32-22-20-31(2)21-23-32)28(33)24-29(35-3)30(26)34/h9-10,24H,4-8,11-23,25H2,1-3H3/b10-9-
  • InChiKey: PFAOMSOCYHTNSH-KTKRTIGZSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[(Z)-heptadec-10-enyl]-5-methoxy-2-[(4-methylpiperazin-1-yl)methyl]-1,4-benzoquinone
  • 3-[(Z)-heptadec-10-enyl]-5-methoxy-2-[(4-methyl-1-piperazinyl)methyl]-1,4-benzoquinone
  • 3-[(Z)-heptadec-10-enyl]-5-methoxy-2-[(4-methylpiperazin-1-yl)methyl]-p-benzoquinone
  • 2-Methoxy-5-(4-methyl-1-piperazinyl) methyl-6- (10-heptadecenyl)-1,4-benzoquinone-(Z)-, hydrochloride hydrate
  • AIDS-009968
  • AIDS009968
  • NSC630732 (2.3 HCL SALT)

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica tyrosin kinase, putative 0.0004 0.0243 0.0243
Brugia malayi Dopamine receptor 0.0007 0.0946 0.1908
Schistosoma mansoni serine/threonine protein kinase 0.0042 1 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0007 0.0946 0.0946
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0007 0.0946 0.1908
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0042 0.9996 0.9996
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0946 0.0946
Brugia malayi plexin A 0.0023 0.4961 1
Schistosoma mansoni hypothetical protein 0.0011 0.198 0.198
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0007 0.0946 0.0946
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0946 0.0946
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Echinococcus granulosus plexin a4 0.0023 0.4961 0.4961
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Echinococcus multilocularis neuropeptide Y receptor 0.0007 0.0946 0.0946
Echinococcus granulosus neuropeptide Y receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Brugia malayi Sema domain containing protein 0.0008 0.1165 0.2348
Entamoeba histolytica protein kinase, putative 0.0042 1 1
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) sema domain-containing protein 0.0008 0.1165 0.2348
Schistosoma mansoni hypothetical protein 0.0008 0.1165 0.1165
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0042 0.9996 0.9996
Onchocerca volvulus 0.0008 0.1165 0.0702
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis neuropeptide s receptor 0.0007 0.0946 0.0946
Schistosoma mansoni opsin-like receptor 0.0007 0.0946 0.0946
Schistosoma mansoni biogenic amine (5HT) receptor 0.0007 0.0946 0.0946
Echinococcus granulosus neuropeptide FF receptor 2 0.0007 0.0946 0.0946
Schistosoma mansoni hypothetical protein 0.0008 0.1165 0.1165
Echinococcus granulosus neuropeptide receptor 0.0007 0.0946 0.0946
Echinococcus granulosus g protein coupled receptor 0.0007 0.0946 0.0946
Schistosoma mansoni neuropeptide receptor 0.0007 0.0946 0.0946
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0007 0.0946 0.1908
Brugia malayi G-protein coupled receptor 0.0007 0.0946 0.1908
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0007 0.0946 0.0946
Echinococcus granulosus biogenic amine 5HT receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0007 0.0946 0.0946
Trichomonas vaginalis conserved hypothetical protein 0.0004 0 0.5
Echinococcus granulosus g-protein coupled receptor 0.0007 0.0946 0.0946
Echinococcus granulosus 7tm_1 domain containing protein 0.0007 0.0946 0.0946
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0007 0.0946 0.0946
Echinococcus granulosus allatostatin A receptor 0.0007 0.0946 0.0946
Entamoeba histolytica protein kinase, putative 0.0042 1 1
Echinococcus granulosus neuropeptides capa receptor 0.0007 0.0946 0.0946
Trichomonas vaginalis conserved hypothetical protein 0.0004 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus granulosus G protein coupled receptor 139 0.0007 0.0946 0.0946
Loa Loa (eye worm) G-protein coupled receptor 0.0007 0.0946 0.1908
Schistosoma mansoni neuropeptide receptor 0.0007 0.0946 0.0946
Echinococcus granulosus orexin receptor type 2 0.0007 0.0946 0.0946
Echinococcus multilocularis hypothetical protein 0.0008 0.1165 0.1165
Schistosoma mansoni neuropeptide receptor 0.0007 0.0946 0.0946
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0007 0.0946 0.0946
Echinococcus granulosus alpha 1A adrenergic receptor 0.0007 0.0946 0.0946
Echinococcus granulosus semaphorin 1A 0.0008 0.1165 0.1165
Brugia malayi hypothetical protein 0.0007 0.0946 0.1908
Echinococcus multilocularis allatostatin A receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0007 0.0946 0.1908
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0004 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0008 0.1165 0.2348
Schistosoma mansoni neuropeptide F-like receptor 0.0007 0.0946 0.0946
Echinococcus granulosus tm gpcr rhodopsin 0.0007 0.0946 0.0946
Brugia malayi putative neuropeptide receptor 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni adenoreceptor 0.0007 0.0946 0.0946
Echinococcus granulosus serotonin receptor 0.0007 0.0946 0.0946
Schistosoma mansoni histamine h1 receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) sema domain-containing protein 0.0008 0.1165 0.2348
Trichomonas vaginalis conserved hypothetical protein 0.0004 0 0.5
Echinococcus multilocularis neuropeptide Y receptor 0.0007 0.0946 0.0946
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0946 0.0946
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0011 0.198 0.3991
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0007 0.0946 0.0946
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0004 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0008 0.1165 0.2348
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Echinococcus multilocularis serotonin receptor 0.0007 0.0946 0.0946
Brugia malayi RE15519p 0.0007 0.0946 0.1908
Schistosoma mansoni hypothetical protein 0.0007 0.0946 0.0946
Loa Loa (eye worm) neuropeptide F receptor 0.0007 0.0946 0.1908
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus granulosus neuropeptide s receptor 0.0007 0.0946 0.0946
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis G protein coupled receptor 139 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus multilocularis orexin receptor type 2 0.0007 0.0946 0.0946
Echinococcus granulosus biogenic amine 5HT receptor 0.0007 0.0946 0.0946
Brugia malayi Serotonin receptor 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus granulosus tachykinin peptides receptor 99D 0.0007 0.0946 0.0946
Loa Loa (eye worm) plexin A 0.0023 0.4961 1
Brugia malayi Dopamine receptor protein 2 0.0007 0.0946 0.1908
Brugia malayi Melatonin receptor type 1A 0.0007 0.0946 0.1908
Schistosoma mansoni plexin 0.0011 0.198 0.198
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus multilocularis sex peptide receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis fmrfamide receptor 0.0007 0.0946 0.0946
Echinococcus granulosus g protein coupled receptor 0.0007 0.0946 0.0946
Brugia malayi Sema domain containing protein 0.0008 0.1165 0.2348
Echinococcus granulosus somatostatin receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis neuropeptide receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0007 0.0946 0.0946
Brugia malayi G-protein coupled receptor 0.0007 0.0946 0.1908
Brugia malayi hypothetical protein 0.0008 0.1165 0.2348
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Brugia malayi larval opioid receptor 0.0007 0.0946 0.1908
Loa Loa (eye worm) melatonin receptor type 1A 0.0007 0.0946 0.1908
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0007 0.0946 0.0946
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0946 0.0946
Brugia malayi putative neuropeptide receptor NPR1 0.0007 0.0946 0.1908
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Echinococcus granulosus neuropeptide receptor 0.0007 0.0946 0.0946
Brugia malayi GnHR receptor homolog 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Brugia malayi Tachykinin-like peptides receptor 99D 0.0007 0.0946 0.1908
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Echinococcus multilocularis G-protein coupled receptor, putative 0.0007 0.0946 0.0946
Schistosoma mansoni opsin-like receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0007 0.0946 0.1908
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0007 0.0946 0.0946
Brugia malayi hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0007 0.0946 0.0946
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0004 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.0004 0.0243 0.0243
Echinococcus granulosus tm gpcr rhodopsin 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Echinococcus multilocularis neuropeptide FF receptor 2 0.0007 0.0946 0.0946
Brugia malayi neuropeptide F receptor 0.0007 0.0946 0.1908
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0007 0.0946 0.0946
Echinococcus multilocularis g protein coupled receptor 0.0007 0.0946 0.0946
Schistosoma mansoni neuropeptide receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus multilocularis dro:myosuppressin receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0008 0.1165 0.2348
Echinococcus granulosus neuropeptides capa receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0008 0.1165 0.2348
Echinococcus granulosus tm gpcr rhodopsin 0.0007 0.0946 0.0946
Echinococcus multilocularis plexin a4 0.0023 0.4961 0.4961
Brugia malayi AKH receptor 0.0007 0.0946 0.1908
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0007 0.0946 0.0946
Trichomonas vaginalis conserved hypothetical protein 0.0004 0 0.5
Echinococcus multilocularis g protein coupled receptor 0.0007 0.0946 0.0946
Echinococcus granulosus semaphorin 5B 0.0008 0.1165 0.1165
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0007 0.0946 0.1908
Brugia malayi Serotonin receptor 0.0007 0.0946 0.1908
Schistosoma mansoni hypothetical protein 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Brugia malayi hypothetical protein 0.0007 0.0946 0.1908
Brugia malayi follicle stimulating hormone receptor 0.0007 0.0946 0.1908
Brugia malayi sulfakinin receptor protein 0.0007 0.0946 0.1908
Brugia malayi hypothetical protein 0.0007 0.0946 0.1908
Trichomonas vaginalis conserved hypothetical protein 0.0004 0 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0004 0 0.5
Schistosoma mansoni myosin xvIII 0.0007 0.0946 0.0946
Schistosoma mansoni growth hormone secretagogue receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus multilocularis somatostatin receptor 0.0007 0.0946 0.0946
Brugia malayi neuropeptide F receptor 0.0007 0.0946 0.1908
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Brugia malayi hypothetical protein 0.0008 0.1165 0.2348
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0004 0 0.5
Echinococcus granulosus g protein coupled receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0008 0.1165 0.2348
Schistosoma mansoni opsin-like receptor 0.0007 0.0946 0.0946
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0042 1 1
Schistosoma mansoni neuropeptide F-like receptor 0.0007 0.0946 0.0946
Schistosoma mansoni amine GPCR 0.0007 0.0946 0.0946
Echinococcus granulosus neuropeptide Y receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis neuropeptides capa receptor 0.0007 0.0946 0.0946
Echinococcus granulosus fmrfamide receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Brugia malayi ORL1-like opioid receptor 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus multilocularis fmrfamide receptor 0.0007 0.0946 0.0946
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0007 0.0946 0.0946
Brugia malayi hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) G-protein coupled receptor 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0007 0.0946 0.0946
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0007 0.0946 0.1908
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0004 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0946 0.0946
Schistosoma mansoni hypothetical protein 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Brugia malayi hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni semaphorin 5-related 0.0008 0.1165 0.1165
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0007 0.0946 0.0946
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Loa Loa (eye worm) neuropeptide F receptor 0.0007 0.0946 0.1908
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0007 0.0946 0.0946
Schistosoma mansoni amine GPCR 0.0007 0.0946 0.0946
Echinococcus granulosus sex peptide receptor 0.0007 0.0946 0.0946
Schistosoma mansoni biogenic amine receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni biogenic amine (5HT) receptor 0.0007 0.0946 0.0946
Echinococcus granulosus hypothetical protein 0.0007 0.0946 0.0946
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0007 0.0946 0.0946
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0007 0.0946 0.0946
Brugia malayi hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni alpha-1 adrenergic receptor 0.0007 0.0946 0.0946
Echinococcus granulosus neuropeptide receptor A26 0.0007 0.0946 0.0946
Schistosoma mansoni hypothetical protein 0.0007 0.0946 0.0946
Echinococcus multilocularis neuropeptide receptor A26 0.0007 0.0946 0.0946
Echinococcus granulosus dro:myosuppressin receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Brugia malayi Dopamine receptor protein 1 0.0007 0.0946 0.1908
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Echinococcus granulosus peptide allatostatin:somatostatin 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni amine GPCR 0.0007 0.0946 0.0946
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0007 0.0946 0.0946
Trichomonas vaginalis conserved hypothetical protein 0.0004 0 0.5
Echinococcus multilocularis neuropeptides capa receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni biogenic amine receptor 0.0007 0.0946 0.0946
Schistosoma mansoni biogenic amine receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) TYRA-2 protein 0.0007 0.0946 0.1908
Onchocerca volvulus 0.0019 0.4053 1
Brugia malayi hypothetical protein 0.0007 0.0946 0.1908
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0946 0.0946
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Echinococcus granulosus 7TM GPCR rhodopsin 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0019 0.4053 0.8169
Echinococcus multilocularis neuropeptide receptor 0.0007 0.0946 0.0946
Brugia malayi hypothetical protein 0.0007 0.0946 0.1908
Echinococcus multilocularis g protein coupled receptor 0.0007 0.0946 0.0946
Schistosoma mansoni neuropeptide f receptor 76f 0.0007 0.0946 0.0946
Schistosoma mansoni amine GPCR 0.0007 0.0946 0.0946
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Brugia malayi hypothetical protein 0.0007 0.0946 0.1908
Echinococcus multilocularis g-protein coupled receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Brugia malayi G protein-coupled receptor F59B2.13 0.0007 0.0946 0.1908
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0946 0.0946
Brugia malayi G protein-coupled receptor 0.0007 0.0946 0.1908
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0007 0.0946 0.0946
Echinococcus multilocularis serotonin receptor 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0008 0.1165 0.2348
Schistosoma mansoni plexin 0.0019 0.4053 0.4053
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0007 0.0946 0.0946
Echinococcus multilocularis semaphorin 5B 0.0008 0.1165 0.1165
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0007 0.0946 0.0946
Schistosoma mansoni amine GPCR 0.0007 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0007 0.0946 0.1908
Brugia malayi Plexin repeat family protein 0.0019 0.4053 0.8169
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0007 0.0946 0.1908
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0007 0.0946 0.0946

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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