Detailed information for compound 1659438

Basic information

Technical information
  • TDR Targets ID: 1659438
  • Name: N-(5-phenyl-1,3,4-oxadiazol-2-yl)-5,6,7,8-tet rahydronaphthalene-2-carboxamide
  • MW: 319.357 | Formula: C19H17N3O2
  • H donors: 1 H acceptors: 3 LogP: 3.96 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccc2c(c1)CCCC2)Nc1nnc(o1)c1ccccc1
  • InChi: 1S/C19H17N3O2/c23-17(16-11-10-13-6-4-5-9-15(13)12-16)20-19-22-21-18(24-19)14-7-2-1-3-8-14/h1-3,7-8,10-12H,4-6,9H2,(H,20,22,23)
  • InChiKey: NCMFSDABENSELJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(5-phenyl-1,3,4-oxadiazol-2-yl)tetralin-6-carboxamide
  • N-(5-phenyl-1,3,4-oxadiazol-2-yl)-6-tetralincarboxamide
  • ZINC04276190

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0179 0.0972 0.69
Onchocerca volvulus Neuropeptide F receptor homolog 0.0179 0.0972 0.69
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.0972 1
Echinococcus granulosus g protein coupled receptor 0.0179 0.0972 0.0972
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.0972 0.0965
Schistosoma mansoni hypothetical protein 0.0176 0.095 0.9773
Schistosoma mansoni neuropeptide F-like receptor 0.0179 0.0972 1
Brugia malayi Serotonin receptor 0.0179 0.0972 0.8012
Brugia malayi G protein-coupled receptor 0.0179 0.0972 0.8012
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0179 0.0972 1
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Onchocerca volvulus 0.0179 0.0972 0.69
Echinococcus multilocularis somatostatin receptor 0.0179 0.0972 0.0965
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.0972 0.0972
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Schistosoma mansoni hypothetical protein 0.0179 0.0972 1
Schistosoma mansoni biogenic amine receptor 0.0179 0.0972 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.0972 0.0972
Brugia malayi GnHR receptor homolog 0.0179 0.0972 0.8012
Brugia malayi sulfakinin receptor protein 0.0179 0.0972 0.8012
Echinococcus granulosus G protein coupled receptor 139 0.0179 0.0972 0.0972
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0179 0.0972 0.0972
Echinococcus granulosus neuropeptide receptor 0.0179 0.0972 0.0972
Echinococcus multilocularis neuropeptide Y receptor 0.0179 0.0972 0.0965
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.0972 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.0972 1
Echinococcus multilocularis geminin 0.0176 0.095 0.0943
Onchocerca volvulus 0.0179 0.0972 0.69
Onchocerca volvulus 0.0179 0.0972 0.69
Echinococcus granulosus tachykinin peptides receptor 99D 0.0179 0.0972 0.0972
Schistosoma mansoni neuropeptide f receptor 76f 0.0179 0.0972 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0179 0.0972 0.0965
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0179 0.0972 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0179 0.0972 1
Onchocerca volvulus 0.0051 0.014 0.0947
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Echinococcus multilocularis neuropeptides capa receptor 0.0179 0.0972 0.0965
Loa Loa (eye worm) neuropeptide F receptor 0.0179 0.0972 0.8012
Schistosoma mansoni growth hormone secretagogue receptor 0.0179 0.0972 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0179 0.0972 0.0972
Schistosoma mansoni amine GPCR 0.0179 0.0972 1
Brugia malayi Pre-SET motif family protein 0.0216 0.1211 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0179 0.0972 0.0965
Brugia malayi RE15519p 0.0179 0.0972 0.8012
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0179 0.0972 0.0965
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Schistosoma mansoni neuropeptide receptor 0.0179 0.0972 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.0972 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Echinococcus multilocularis neuropeptide receptor 0.0179 0.0972 0.0965
Brugia malayi hypothetical protein 0.0179 0.0972 0.8012
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.074 0.6089
Echinococcus multilocularis neuropeptide Y receptor 0.0179 0.0972 0.0965
Schistosoma mansoni amine GPCR 0.0179 0.0972 1
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Brugia malayi G-protein coupled receptor 0.0179 0.0972 0.8012
Schistosoma mansoni biogenic amine receptor 0.0179 0.0972 1
Onchocerca volvulus 0.0179 0.0972 0.69
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Onchocerca volvulus 0.0179 0.0972 0.69
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0049 0.0041
Echinococcus multilocularis serotonin receptor 0.0179 0.0972 0.0965
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Echinococcus granulosus g protein coupled receptor 0.0179 0.0972 0.0972
Brugia malayi hypothetical protein 0.0037 0.0049 0.0344
Giardia lamblia Hypothetical protein 0.0083 0.0345 0.5
Schistosoma mansoni myosin xvIII 0.0179 0.0972 1
Brugia malayi Dopamine receptor protein 1 0.0179 0.0972 0.8012
Brugia malayi follicle stimulating hormone receptor 0.0179 0.0972 0.8012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0179 0.0972 1
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.014 0.1373
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0179 0.0972 0.8012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.0972 0.0965
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0179 0.0972 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0179 0.0972 0.0965
Echinococcus multilocularis sex peptide receptor 0.0179 0.0972 0.0965
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0179 0.0972 1
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Onchocerca volvulus 0.0179 0.0972 0.69
Brugia malayi hypothetical protein 0.0179 0.0972 0.8012
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0083 0.0345 0.0338
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.074 0.0733
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.0972 0.0972
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.074 0.7599
Echinococcus multilocularis serotonin receptor 0.0179 0.0972 0.0965
Echinococcus multilocularis fmrfamide receptor 0.0179 0.0972 0.0965
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.0972 1
Schistosoma mansoni biogenic amine receptor 0.0179 0.0972 1
Brugia malayi Dopamine receptor protein 2 0.0179 0.0972 0.8012
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.0083 0.0345 0.0338
Brugia malayi hypothetical protein 0.0179 0.0972 0.8012
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0179 0.0972 0.8012
Brugia malayi hypothetical protein 0.0179 0.0972 0.8012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.074 0.074
Onchocerca volvulus 0.0179 0.0972 0.69
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Brugia malayi hypothetical protein 0.0179 0.0972 0.8012
Schistosoma mansoni hypothetical protein 0.0179 0.0972 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0179 0.0972 1
Echinococcus granulosus neuropeptide Y receptor 0.0179 0.0972 0.0972
Echinococcus granulosus neuropeptide receptor 0.0179 0.0972 0.0972
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.1211 1
Echinococcus granulosus allatostatin A receptor 0.0179 0.0972 0.0972
Brugia malayi hypothetical protein 0.0179 0.0972 0.8012
Echinococcus multilocularis G protein coupled receptor 139 0.0179 0.0972 0.0965
Echinococcus multilocularis G-protein coupled receptor, putative 0.0179 0.0972 0.0965
Echinococcus granulosus alpha 1A adrenergic receptor 0.0179 0.0972 0.0972
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.074 0.7599
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Echinococcus granulosus geminin 0.0176 0.095 0.095
Echinococcus granulosus 7TM GPCR rhodopsin 0.0179 0.0972 0.0972
Echinococcus multilocularis solute carrier family 28 0.1567 1 1
Schistosoma mansoni opsin-like receptor 0.0179 0.0972 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0179 0.0972 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.0972 0.0972
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0083 0.0345 0.2805
Echinococcus granulosus g-protein coupled receptor 0.0179 0.0972 0.0972
Brugia malayi larval opioid receptor 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Brugia malayi Serotonin receptor 0.0179 0.0972 0.8012
Echinococcus granulosus equilibrative nucleoside transporter 3 0.0083 0.0345 0.0345
Brugia malayi Nucleoside transporter family protein 0.0083 0.0345 0.2805
Schistosoma mansoni neuropeptide F-like receptor 0.0179 0.0972 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0179 0.0972 0.0965
Echinococcus multilocularis neuropeptide s receptor 0.0179 0.0972 0.0965
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0179 0.0972 0.0965
Echinococcus granulosus equilibrative nucleoside transporter 0.0083 0.0345 0.0345
Echinococcus multilocularis g protein coupled receptor 0.0179 0.0972 0.0965
Brugia malayi Melatonin receptor type 1A 0.0179 0.0972 0.8012
Echinococcus granulosus sex peptide receptor 0.0179 0.0972 0.0972
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.0972 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.0972 0.0965
Echinococcus granulosus neuropeptide Y receptor 0.0179 0.0972 0.0972
Loa Loa (eye worm) melatonin receptor type 1A 0.0179 0.0972 0.8012
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.0972 0.0972
Onchocerca volvulus 0.0179 0.0972 0.69
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0179 0.0972 0.8012
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0049 0.0049
Echinococcus granulosus tm gpcr rhodopsin 0.0179 0.0972 0.0972
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0051 0.014 0.11
Echinococcus multilocularis orexin receptor type 2 0.0179 0.0972 0.0965
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0179 0.0972 0.0965
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0179 0.0972 0.0972
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0179 0.0972 0.0965
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0179 0.0972 0.0965
Brugia malayi putative neuropeptide receptor 0.0179 0.0972 0.8012
Schistosoma mansoni opsin-like receptor 0.0179 0.0972 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0179 0.0972 0.0965
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0179 0.0972 0.0965
Brugia malayi G-protein coupled receptor 0.0179 0.0972 0.8012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.0972 0.0965
Loa Loa (eye worm) neuropeptide F receptor 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0083 0.0345 0.2805
Schistosoma mansoni amine GPCR 0.0179 0.0972 1
Echinococcus granulosus dro:myosuppressin receptor 0.0179 0.0972 0.0972
Echinococcus granulosus hypothetical protein 0.0179 0.0972 0.0972
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Onchocerca volvulus 0.0179 0.0972 0.69
Echinococcus multilocularis g protein coupled receptor 0.0179 0.0972 0.0965
Schistosoma mansoni hypothetical protein 0.0179 0.0972 1
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Echinococcus granulosus tm gpcr rhodopsin 0.0179 0.0972 0.0972
Echinococcus granulosus neuropeptide s receptor 0.0179 0.0972 0.0972
Brugia malayi putative neuropeptide receptor NPR1 0.0179 0.0972 0.8012
Echinococcus granulosus neuropeptide receptor A26 0.0179 0.0972 0.0972
Echinococcus granulosus 7tm_1 domain containing protein 0.0179 0.0972 0.0972
Echinococcus granulosus tumor protein p63 0.035 0.2087 0.2087
Brugia malayi neuropeptide F receptor 0.0179 0.0972 0.8012
Brugia malayi AKH receptor 0.0179 0.0972 0.8012
Loa Loa (eye worm) G-protein coupled receptor 0.0179 0.0972 0.8012
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0179 0.0972 1
Onchocerca volvulus 0.0179 0.0972 0.69
Echinococcus multilocularis neuropeptide FF receptor 2 0.0179 0.0972 0.0965
Onchocerca volvulus 0.0179 0.0972 0.69
Brugia malayi hypothetical protein 0.0083 0.0345 0.2805
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Schistosoma mansoni histamine h1 receptor 0.0179 0.0972 1
Echinococcus multilocularis neuropeptide receptor 0.0179 0.0972 0.0965
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0179 0.0972 0.8012
Brugia malayi hypothetical protein 0.0179 0.0972 0.8012
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0179 0.0972 0.0965
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0179 0.0972 0.0972
Echinococcus multilocularis neuropeptides capa receptor 0.0179 0.0972 0.0965
Schistosoma mansoni neuropeptide receptor 0.0179 0.0972 1
Echinococcus multilocularis allatostatin A receptor 0.0179 0.0972 0.0965
Onchocerca volvulus 0.0179 0.0972 0.69
Plasmodium vivax SET domain protein, putative 0.0031 0.0007 0.5
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0179 0.0972 0.8012
Onchocerca volvulus 0.0179 0.0972 0.69
Echinococcus granulosus neuropeptide FF receptor 2 0.0179 0.0972 0.0972
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0179 0.0972 0.0965
Onchocerca volvulus 0.0179 0.0972 0.69
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.0972 0.0965
Echinococcus granulosus fmrfamide receptor 0.0179 0.0972 0.0972
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.0972 0.0965
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0179 0.0972 0.8012
Brugia malayi hypothetical protein 0.0179 0.0972 0.8012
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0179 0.0972 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0179 0.0972 0.8012
Brugia malayi G protein-coupled receptor F59B2.13 0.0179 0.0972 0.8012
Echinococcus granulosus biogenic amine 5HT receptor 0.0179 0.0972 0.0972
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0179 0.0972 1
Brugia malayi Dopamine receptor 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Echinococcus granulosus Na+ dependent nucleoside transporter 0.1567 1 1
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Schistosoma mansoni amine GPCR 0.0179 0.0972 1
Echinococcus granulosus tm gpcr rhodopsin 0.0179 0.0972 0.0972
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.0972 0.0965
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0179 0.0972 0.8012
Echinococcus multilocularis sodium:nucleoside cotransporter 2 0.1022 0.6454 0.6452
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Schistosoma mansoni biogenic amine (5HT) receptor 0.0179 0.0972 1
Onchocerca volvulus 0.0179 0.0972 0.69
Echinococcus granulosus neuropeptides capa receptor 0.0179 0.0972 0.0972
Onchocerca volvulus 0.0246 0.1405 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.0972 0.0972
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0179 0.0972 0.0965
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0068 0.0251 0.0244
Schistosoma mansoni hypothetical protein 0.0037 0.0049 0.0429
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.074 0.7599
Brugia malayi Tachykinin-like peptides receptor 99D 0.0179 0.0972 0.8012
Echinococcus granulosus concentrative Na nucleoside cotransporter 0.1567 1 1
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Schistosoma mansoni hypothetical protein 0.0176 0.095 0.9773
Echinococcus multilocularis concentrative Na+ nucleoside cotransporter 0.1567 1 1
Trichomonas vaginalis set domain proteins, putative 0.0246 0.1405 1
Schistosoma mansoni neuropeptide receptor 0.0179 0.0972 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0179 0.0972 0.0972
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0049 0.0429
Entamoeba histolytica nucleoside transporter, putative 0.0083 0.0345 1
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Schistosoma mansoni hypothetical protein 0.0179 0.0972 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0179 0.0972 0.0965
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.074 0.074
Loa Loa (eye worm) hypothetical protein 0.0083 0.0345 0.2805
Schistosoma mansoni amine GPCR 0.0179 0.0972 1
Echinococcus granulosus somatostatin receptor 0.0179 0.0972 0.0972
Brugia malayi hypothetical protein 0.0179 0.0972 0.8012
Brugia malayi ORL1-like opioid receptor 0.0179 0.0972 0.8012
Schistosoma mansoni adenoreceptor 0.0179 0.0972 1
Echinococcus granulosus serotonin receptor 0.0179 0.0972 0.0972
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0179 0.0972 1
Echinococcus granulosus orexin receptor type 2 0.0179 0.0972 0.0972
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.0972 1
Echinococcus multilocularis neuropeptide receptor A26 0.0179 0.0972 0.0965
Schistosoma mansoni biogenic amine (5HT) receptor 0.0179 0.0972 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.0972 1
Echinococcus multilocularis g-protein coupled receptor 0.0179 0.0972 0.0965
Echinococcus multilocularis g protein coupled receptor 0.0179 0.0972 0.0965
Loa Loa (eye worm) G-protein coupled receptor 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Brugia malayi hypothetical protein 0.0179 0.0972 0.8012
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0007 0.5
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.074 0.0733
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0179 0.0972 0.0972
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0179 0.0972 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0179 0.0972 0.8012
Schistosoma mansoni neuropeptide receptor 0.0179 0.0972 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.074 0.6089
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0179 0.0972 0.0972
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Echinococcus multilocularis fmrfamide receptor 0.0179 0.0972 0.0965
Echinococcus multilocularis rhodopsin orphan GPCR 0.0179 0.0972 0.0965
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0179 0.0972 0.0972
Echinococcus multilocularis tumor protein p63 0.035 0.2087 0.2081
Echinococcus granulosus biogenic amine 5HT receptor 0.0179 0.0972 0.0972
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0083 0.0345 0.2415
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0179 0.0972 1
Loa Loa (eye worm) TYRA-2 protein 0.0179 0.0972 0.8012
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0083 0.0345 0.2415
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0179 0.0972 0.69
Schistosoma mansoni opsin-like receptor 0.0179 0.0972 1
Echinococcus granulosus neuropeptides capa receptor 0.0179 0.0972 0.0972
Brugia malayi neuropeptide F receptor 0.0179 0.0972 0.8012
Onchocerca volvulus 0.0179 0.0972 0.69
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0179 0.0972 1
Loa Loa (eye worm) hypothetical protein 0.0179 0.0972 0.8012
Echinococcus granulosus g protein coupled receptor 0.0179 0.0972 0.0972

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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