Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cyclin l | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | CYL-1 protein | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma cruzi | mitotic cyclin, putative | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma brucei | mitotic cyclin | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.2883 | 0.2883 |
Trichomonas vaginalis | cyclins, putative | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0033 | 0.1387 | 0.1387 |
Giardia lamblia | Hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0051 | 0.289 | 0.289 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Leishmania major | mitotic cyclin, putative | 0.0033 | 0.1387 | 0.1387 |
Toxoplasma gondii | hypothetical protein | 0.0033 | 0.1387 | 0.191 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.2883 | 0.2883 |
Echinococcus multilocularis | cyclin y | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Schistosoma mansoni | g1/s-specific cyclin C | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclin k | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin A, putative | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma cruzi | cyclin 6, putative | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclin A, putative | 0.0135 | 1 | 1 |
Schistosoma mansoni | cyclin d | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.2883 | 0.2883 |
Mycobacterium tuberculosis | Transcriptional regulatory protein | 0.0051 | 0.289 | 0.5 |
Trichomonas vaginalis | cyclin B3, putative | 0.0135 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclin B | 0.0135 | 1 | 1 |
Entamoeba histolytica | Sir2 family transcriptional regulator, putative | 0.0051 | 0.289 | 0.289 |
Entamoeba histolytica | cyclin, putative | 0.0135 | 1 | 1 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0135 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | Cyclin L1 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Echinococcus granulosus | cyclin G2 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclin G2 | 0.0033 | 0.1387 | 0.1387 |
Toxoplasma gondii | cyclin domain protein, cyclin H family protein | 0.0033 | 0.1387 | 0.191 |
Echinococcus granulosus | cyclins | 0.0135 | 1 | 1 |
Onchocerca volvulus | 0.0135 | 1 | 1 | |
Echinococcus granulosus | cyclin A3 4 | 0.0033 | 0.1387 | 0.1387 |
Leishmania major | mitotic cyclin, putative | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclins, putative | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin B, putative | 0.0135 | 1 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0135 | 1 | 1 |
Echinococcus granulosus | cyclin | 0.0033 | 0.1387 | 0.1387 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0135 | 1 | 1 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0033 | 0.1387 | 0.1387 |
Plasmodium falciparum | cyclin | 0.0135 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 1 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Mycobacterium leprae | Probable NAD-dependent deacetylase NpdA (Regulatory protein SIR2 homolog) | 0.0034 | 0.1537 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Entamoeba histolytica | cyclin family protein | 0.0135 | 1 | 1 |
Plasmodium falciparum | cyclin 1 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | oligomeric golgi complex subunit 3 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.0135 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0103 | 0.726 | 1 |
Toxoplasma gondii | histone deacetylase SIR2 | 0.0051 | 0.289 | 0.3981 |
Echinococcus granulosus | cdk5 and abl1 enzyme substrate 1 | 0.0033 | 0.1387 | 0.1387 |
Leishmania major | NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe | 0.0051 | 0.289 | 0.289 |
Trichomonas vaginalis | cyclins, putative | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0135 | 1 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Echinococcus granulosus | cyclins | 0.0135 | 1 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cyclin | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Giardia lamblia | Cyclin fold protein 1, putative | 0.0033 | 0.1387 | 0.1387 |
Giardia lamblia | Hypothetical protein | 0.0135 | 1 | 1 |
Trypanosoma cruzi | Silent information regulator 2 related protein 3 | 0.0051 | 0.289 | 0.289 |
Trypanosoma cruzi | mitotic cyclin, putative | 0.0033 | 0.1387 | 0.1387 |
Leishmania major | cyclin 9, putative | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclin y | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclin B3 1 | 0.0135 | 1 | 1 |
Trypanosoma brucei | cyclin 3 | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin D, putative | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin D, putative | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.2883 | 0.2883 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclin G2 | 0.0033 | 0.1387 | 0.1387 |
Entamoeba histolytica | cyclin, domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Plasmodium vivax | cyclin dependent kinase binding protein, putative | 0.0033 | 0.1387 | 0.4797 |
Entamoeba histolytica | cyclin, putative | 0.0135 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0135 | 1 | 1 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | cyclin B3 | 0.0135 | 1 | 1 |
Loa Loa (eye worm) | cyclin C | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin D, putative | 0.0135 | 1 | 1 |
Brugia malayi | Cyclin C | 0.0033 | 0.1387 | 0.1387 |
Plasmodium vivax | hypothetical protein, conserved | 0.0033 | 0.1387 | 0.4797 |
Trypanosoma brucei | cyclin dependent kinase-binding protein, putative | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | cyclin B | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0051 | 0.289 | 0.289 |
Echinococcus multilocularis | cyclin A3 4 | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | cyclin fold protein 1 variant b | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclin t1 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclin b3 | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin B3, putative | 0.0033 | 0.1387 | 0.1387 |
Entamoeba histolytica | cyclin family protein | 0.0135 | 1 | 1 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | oligomeric golgi complex subunit 3 | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | Cyclin fold protein | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | cyclin fold protein 1 variant b | 0.0033 | 0.1387 | 0.1387 |
Plasmodium falciparum | cyclin dependent kinase binding protein, putative | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Giardia lamblia | Transcriptional regulator, Sir2 family | 0.0051 | 0.289 | 0.289 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0051 | 0.289 | 0.289 |
Mycobacterium ulcerans | NAD-dependent deacetylase | 0.0051 | 0.289 | 1 |
Schistosoma mansoni | cyclins | 0.0135 | 1 | 1 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0135 | 1 | 1 |
Echinococcus granulosus | cyclin B | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0135 | 1 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0135 | 1 | 1 |
Leishmania major | cyclin | 0.0135 | 1 | 1 |
Entamoeba histolytica | cyclin C, putative | 0.0033 | 0.1387 | 0.1387 |
Toxoplasma gondii | cyclin 4, putative | 0.0033 | 0.1387 | 0.191 |
Echinococcus multilocularis | cyclin t1 | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1542 | 0.1542 |
Echinococcus multilocularis | cyclin B3 1 | 0.0135 | 1 | 1 |
Toxoplasma gondii | cyclin dependent kinase binding protein | 0.0033 | 0.1387 | 0.191 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0051 | 0.289 | 0.289 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.1542 | 0.1542 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1542 | 0.1542 |
Echinococcus granulosus | cyclins | 0.0135 | 1 | 1 |
Plasmodium vivax | cyclin homologue, putative | 0.0033 | 0.1387 | 0.4797 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Toxoplasma gondii | cyclin, N-terminal domain-containing protein | 0.0033 | 0.1387 | 0.191 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclin k | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclins | 0.0135 | 1 | 1 |
Echinococcus granulosus | Cyclin L1 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclins | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclin y | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0033 | 0.1387 | 0.1387 |
Giardia lamblia | Cyclin A | 0.0135 | 1 | 1 |
Schistosoma mansoni | cyclin k | 0.0033 | 0.1387 | 0.1387 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma brucei | Silent information regulator 2 related protein 3 | 0.0051 | 0.289 | 0.289 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma cruzi | Silent information regulator 2 related protein 3 | 0.0051 | 0.289 | 0.289 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Schistosoma mansoni | cyclin G | 0.0033 | 0.1387 | 0.1387 |
Plasmodium vivax | cyclin 4, putative | 0.0033 | 0.1387 | 0.4797 |
Entamoeba histolytica | cyclin, domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclins, putative | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0135 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Plasmodium vivax | NAD-dependent deacetylase, putative | 0.0051 | 0.289 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cyclin b3 | 0.0135 | 1 | 1 |
Schistosoma mansoni | cyclin G2 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclins | 0.0135 | 1 | 1 |
Plasmodium falciparum | transcriptional regulatory protein sir2a | 0.0051 | 0.289 | 0.289 |
Trichomonas vaginalis | cyclin B3, putative | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma brucei | cyclin 9 | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0135 | 1 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cdk5 and abl1 enzyme substrate 1 | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma cruzi | cyclin 9, putative | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclin G2 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclin y | 0.0033 | 0.1387 | 0.1387 |
Giardia lamblia | Cyclin B-like protein | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin B, putative | 0.0135 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.