Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.003 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.7759 | 0.7759 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.7759 | 0.7759 |
Echinococcus granulosus | cathepsin l1 | 0.0027 | 0.7759 | 0.7759 |
Onchocerca volvulus | Cathepsin F homolog | 0.0027 | 0.7759 | 0.7759 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.003 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.7759 | 0.7759 |
Onchocerca volvulus | 0.0027 | 0.7759 | 0.7759 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.003 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0027 | 0.7759 | 0.7759 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Onchocerca volvulus | 0.0027 | 0.7759 | 0.7759 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Plasmodium vivax | RNA helicase-1, putative | 0.003 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.7759 | 0.7759 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.003 | 1 | 1 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.003 | 1 | 1 |
Treponema pallidum | ATP-dependent RNA helicase | 0.003 | 1 | 0.5 |
Onchocerca volvulus | 0.0027 | 0.7759 | 0.7759 | |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 1 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0027 | 0.7759 | 0.7759 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.003 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0027 | 0.7759 | 0.7759 |
Onchocerca volvulus | 0.0027 | 0.7759 | 0.7759 | |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.003 | 1 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0027 | 0.7759 | 0.7759 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.7759 | 0.7759 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.7759 | 0.7759 |
Onchocerca volvulus | Cathepsin L homolog | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.003 | 1 | 1 |
Onchocerca volvulus | 0.0027 | 0.7759 | 0.7759 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.003 | 1 | 1 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.003 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.7759 | 0.7759 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.7759 | 0.7759 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.003 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.003 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.003 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.003 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0027 | 0.7759 | 0.7759 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.003 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0027 | 0.7759 | 0.7759 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.003 | 1 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.003 | 1 | 1 |
Onchocerca volvulus | 0.0027 | 0.7759 | 0.7759 | |
Onchocerca volvulus | 0.0027 | 0.7759 | 0.7759 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0027 | 0.7759 | 0.7759 |
Mycobacterium tuberculosis | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) | 0.003 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.7759 | 0.7759 |
Loa Loa (eye worm) | ctsf protein | 0.0027 | 0.7759 | 0.7759 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.003 | 1 | 1 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.003 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.7759 | 0.7759 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.