Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.0754 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.8073 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0525 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.2139 | 0.1681 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.4678 | 0.4619 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.4678 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.8073 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.8073 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.2139 | 0.1704 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.2139 | 0.372 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.2139 | 0.2052 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.4678 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.4393 | 0.4856 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0634 | 0.0531 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.2139 | 0.1681 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.2139 | 0.372 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.2139 | 0.372 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.2139 | 0.1704 |
Onchocerca volvulus | 0.0028 | 0.4393 | 0.5 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.8073 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.5326 | 0.615 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.2139 | 0.372 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.2139 | 0.2052 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.2139 | 0.2052 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.5326 | 0.616 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.8867 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.4678 | 0.4619 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.0754 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.2139 | 0.372 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.4393 | 0.4331 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.5326 | 0.5275 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.2139 | 0.2052 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.2139 | 0.372 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.4393 | 0.4842 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0525 | 1 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 22749421 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.