Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | histone deacetylase 2, putative | 0.0064 | 0.3512 | 0.619 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0064 | 0.3512 | 0.619 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0083 | 0.5284 | 1 |
Echinococcus granulosus | histone deacetylase | 0.0064 | 0.3512 | 0.6646 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0064 | 0.3512 | 0.619 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0083 | 0.5284 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0083 | 0.5284 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0083 | 0.5284 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0083 | 0.5284 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0083 | 0.5284 | 0.5 |
Trypanosoma brucei | histone deacetylase 1 | 0.0083 | 0.5284 | 1 |
Trypanosoma brucei | histone deacetylase 3 | 0.0064 | 0.3512 | 0.619 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0083 | 0.5284 | 1 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0064 | 0.3512 | 0.6646 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0071 | 0.4143 | 0.7547 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0083 | 0.5284 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0083 | 0.5284 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0064 | 0.3512 | 0.3229 |
Echinococcus granulosus | histone deacetylase 6 | 0.0064 | 0.3512 | 0.6646 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0083 | 0.5284 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0071 | 0.4143 | 0.784 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0063 | 0.3365 | 0.5875 |
Plasmodium vivax | histone deacetylase, putative | 0.0064 | 0.3512 | 0.619 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0071 | 0.4143 | 0.784 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.5284 | 0.5079 |
Entamoeba histolytica | histone deacetylase, putative | 0.0083 | 0.5284 | 0.5 |
Brugia malayi | Histone deacetylase 1 | 0.0083 | 0.5284 | 0.4966 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0083 | 0.5284 | 0.5079 |
Giardia lamblia | Histone deacetylase | 0.0083 | 0.5284 | 0.5 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0064 | 0.3512 | 0.619 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0134 | 1 | 1 |
Trypanosoma brucei | histone deacetylase 4 | 0.0064 | 0.3512 | 0.619 |
Schistosoma mansoni | histone deacetylase | 0.0083 | 0.5284 | 1 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0083 | 0.5284 | 0.5079 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0063 | 0.3365 | 0.6369 |
Echinococcus granulosus | histone deacetylase 3 | 0.0083 | 0.5284 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0064 | 0.3512 | 0.3074 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0083 | 0.5284 | 0.5 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0083 | 0.5284 | 0.4966 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0083 | 0.5284 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0083 | 0.5284 | 1 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0033 | 0.0632 | 0.5 |
Echinococcus granulosus | histone deacetylase 6 | 0.0064 | 0.3512 | 0.6646 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0064 | 0.3512 | 0.6646 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0083 | 0.5284 | 0.4966 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0064 | 0.3512 | 0.619 |
Echinococcus granulosus | histone deacetylase 8 | 0.0033 | 0.0632 | 0.1197 |
Trypanosoma brucei | histone deacetylase, putative | 0.0064 | 0.3512 | 0.619 |
Leishmania major | histone deacetylase, putative | 0.0083 | 0.5284 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0083 | 0.5284 | 1 |
Loa Loa (eye worm) | histone deacetylase | 0.0064 | 0.3512 | 0.3229 |
Plasmodium falciparum | histone deacetylase 1 | 0.0083 | 0.5284 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0064 | 0.3512 | 0.619 |
Echinococcus multilocularis | histone deacetylase | 0.0064 | 0.3512 | 0.6646 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0134 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0083 | 0.5284 | 1 |
Echinococcus granulosus | histone deacetylase 1 | 0.0083 | 0.5284 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0064 | 0.3512 | 0.3074 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0033 | 0.0632 | 0.0224 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0083 | 0.5284 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0064 | 0.3512 | 0.619 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0033 | 0.0632 | 0.1197 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1048 | 0.0658 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0063 | 0.3365 | 0.6369 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0064 | 0.3512 | 0.6646 |
Echinococcus granulosus | histone deacetylase 7 | 0.0064 | 0.3512 | 0.6646 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0632 | 0.0224 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0083 | 0.5284 | 0.5 |
Schistosoma mansoni | histone deacetylase | 0.0083 | 0.5284 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.