Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.1077 | 1 | 1 | |
Plasmodium vivax | hexokinase, putative | 0.1077 | 1 | 0.5 |
Entamoeba histolytica | hexokinase 2 | 0.1077 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.1077 | 1 | 0.5 |
Treponema pallidum | hexokinase (hxk) | 0.1077 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.1077 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.1077 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.1077 | 1 | 0.5 |
Trypanosoma brucei | hexokinase, putative | 0.1077 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0676 | 0.4604 | 0.4604 |
Echinococcus granulosus | hexokinase | 0.1077 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase type 2 | 0.1077 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.0123 | 0.0123 |
Brugia malayi | Hexokinase family protein | 0.1077 | 1 | 1 |
Echinococcus granulosus | hexokinase type 2 | 0.1077 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.1077 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.1077 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.0123 | 0.0123 |
Echinococcus granulosus | hexokinase | 0.1077 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.1077 | 1 | 1 |
Entamoeba histolytica | hexokinase 1 | 0.1077 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.1077 | 1 | 0.5 |
Plasmodium falciparum | hexokinase | 0.1077 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.1077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0735 | 0.5396 | 0.5396 |
Trypanosoma cruzi | hexokinase, putative | 0.1077 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.1077 | 1 | 0.5 |
Onchocerca volvulus | 0.1077 | 1 | 1 | |
Loa Loa (eye worm) | hexokinase | 0.0676 | 0.4604 | 0.4604 |
Echinococcus multilocularis | hexokinase | 0.1077 | 1 | 0.5 |
Onchocerca volvulus | 0.1077 | 1 | 1 | |
Toxoplasma gondii | hexokinase | 0.1077 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase type II | 0.1077 | 1 | 1 |
Schistosoma mansoni | hexokinase | 0.1077 | 1 | 0.5 |
Brugia malayi | hexokinase type II | 0.0343 | 0.0123 | 0.0123 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.